脑干听觉诱发电位检测早期诊断2型糖尿病患者颅神经亚临床损害的临床价值  

Clinical value of brainstem auditory evoked potential detection in the early diagnosis of subclinical neuropathy of patients with type 2 diabetes mellitus

作　　者：王竹梅[1] 刘汉鹏[2] 魏希进[1] 

机构地区：[1]山东中医药大学附属医院,济南250011 [2]山东中医药大学

出　　处：《山东医药》2013年第33期7-8,11,共3页Shandong Medical Journal

基　　金：山东省科技厅科学技术发展计划项目(2010YDI5013)

摘　　要：目的探讨脑干听觉诱发电位（BAEP）检测早期诊断2型糖尿病患者颅神经亚临床损害的临床价值。方法选择30例2型糖尿病患者（糖尿病组）和30例健康查体者（对照组），均应用MEB0200K型肌电图诱发电位仪在室温20～25℃的隔音屏蔽室中进行BAEP检测，记录其Ⅰ～Ⅲ及Ⅲ～Ⅴ波峰间潜伏期。结果糖尿病组BAEP的Ⅰ-Ⅲ波峰间潜伏期为（2．44±0．31）ms、Ⅲ～Ⅴ波峰间潜伏期为（1．99±0．37）ms，对照组分别为（2．22±0．19）、（1．80±0．21）ms，糖尿病组的Ⅰ～Ⅲ、Ⅲ-Ⅴ波峰间潜伏期较对照组延长（P均〈0．01）。结论BAEP检测有助于早期诊断2型糖尿病患者的颅神经、脑干受损及亚临床损害。Objective To investigate the clinical value of brainstem auditory evoked potential （BAEP） detection in the early diagnosis of subclinical neuropathy of patients with type 2 diabetes mellitus. Methods BAEP detection was conducted in 30 patients with type 2 diabetes mellitus （DM group） and 30 eases of healthy people （control group） by using MEB-9200K type electromyography evoked potential instrument at the temperature of 20-25 ℃ in the insulation shielding room. In addition, Ⅰ- Ⅲ and Ⅲ- Ⅴ inter peak latency （IPL） of BAEP was recorded. Results In the DM group, Ⅰ- Ⅲ IPL was （2.44±0.31） ms, Ⅲ-Ⅴ IPL was （1.99±0.37） ms, and those in the control group were （2.22 ±0. 19） and （ 1.80 ± 0.21 ） ms, respectively. Ⅰ-Ⅲ, Ⅲ-Ⅴ IPL of BAEP in the BM group was significantly prolonged compared with that in the control group （ P 〈 0.05 ）. Conclusion The BAEP detection is helpful to the early diagnosis of cranial nerves, brainstem and subclinical lesions of patients with type 2 diabetes mellitus.

关 键 词：糖尿病 2型 颅神经损害 脑干听觉诱发电位 

分 类 号：R587.1[医药卫生—内分泌]