补肾活血化痰组方治疗青春期多囊卵巢综合征41例  

Clinical Efficacy of Kidney-Tonifying,Blood-Activating,and Phlegm-Eliminating Prescription in Treatment of Adolescent Polycystic Ovary Syndrome:A Report of 41 Cases

作　　者：王针织[1,2] 孙帅[1] 俞超芹[1] 韩洁[1] 翟东霞[1] 

机构地区：[1]第二军医大学长海医院中医系,上海200433 [2]上海市浦东新区中医医院,上海201200

出　　处：《安徽中医学院学报》2013年第5期24-27,共4页Journal of Anhui Traditional Chinese Medical College

基　　金：国家自然科学基金项目(81001535);上海市中医药发展办公室杏林新星计划项目(ZYSNXD011-RC-XLXX-20130034)

摘　　要：目的观察补肾活血化疾组方治疗青春期多囊卵巢综合征（polycysticovarysyndrome，PCOS）的临床疗效．方法收集年龄为13-20岁的青春期PCOS患者41例，采用补肾活血化痰组方进行治疗，观察患者治疗前后月经周期、排卵、肥胖、多毛、黑棘皮症、痤疮等临床症状及血睾酮（testosterone，T）、胰岛素（in—siilill．Ins）、黄体生成激素（luteotrophic hormaonc，LH）、卵泡刺激素（folliclestimulatinghormone．FSH）、雌二醇（estradiol．E2）的变化情况。结果补肾活血化痰组方能明显降低患者的血T、Ins和LH水平（P〈0．05，或，P〈0．01），改善患者的月经失调、癌疮等临床症状（P〈0．05，或P〈0．01）。结论补肾活血化痰组方治疗青春期PCOS有较好的临床疗效。Objective To observe tile clinical efficacy of kidney tonifying, blood-activating, and phlegm e liminating （KTBAPE） prescription in the treatment of adolescent polycystic ovary syndrome （PCOS）. Methods Forty-one adolescent PCOS patients aged 13 20 years were enrolled in the study. These patients were treated with KTBAPE prescription. The therapeutic effects were assessed based on clinical symptoms including menstrual cycle, ovulation,obesity,hirsutism, acanthosis nigricans, and acne and serum levels of testosterone （T）, insulin （Ins）, luteotropic hormone （LH）, follicle stimulating hormone, and estradiol. Results KTBAPE prescription significantly decreased serum levels of T, Ins, and LH （P〈0.05 or P〈0.01） and significantly improved the clinical symptoms including menstrual disorder and acne （P〈0.05 or P〈0.01）. Conclusion KTBAPE prescription has good clinical efficacy in the treatment of adolescent PCOS.

关 键 词：青春期多囊卵巢综合征 补肾活血化痰组方 性激素 

分 类 号：R711.75[医药卫生—妇产科学]