结膜相关淋巴组织和哈氏腺免疫协同关系的研究Ⅰ.结膜相关淋巴组织缺失对哈氏腺点眼免疫应答的影响  

Studies on immune relationship between conjunctiva associated lymphoid tissue and Harderian gland

作　　者：王彩虹[1] 高齐瑜[1] 

机构地区：[1]中国农业大学动物医学院，北京 海淀 100089

出　　处：《中国兽医杂志》2000年第11期9-11,共3页Chinese Journal of Veterinary Medicine

基　　金：国家自然科学基金编号:39370533

摘　　要：采用 EL ISA、免疫组织化学方法、手术切除结膜相关淋巴组织 ( Conjunctiva- associated L ymphoidTissue,CAL T)法对结膜相关淋巴组织和哈氏腺 ( Harderian Gland,HG)在点眼免疫应答过程中的相互协同关系进行了研究。研究发现 ,采用外科手术于 1日龄切除结膜相关淋巴组织后切除组点眼免疫后泪液中 NDV-特异性 Ig A、Ig M型抗体滴度及哈氏腺中 Ig A、Ig M型浆细胞的数量均显著低于正常免疫组 ( P<0 .0 5) ,而两组间泪液中 NDV-特异性 Ig G型抗体滴度及哈氏腺中 IgImmune relationship between conjunctiva associated lymphoid tissue (CALT) and Harderian Gland(HG) during the ocular immune response was studied. It was found that the titre of NDV specific IgA、IgM in tears and the number of plasma cells of IgA、 IgM isotype in HG of the CALT excised group were significantly lower than that of the untreated group (P<0.05). But there were no significantly differences in the titre of NDV specific IgG in tears and the number of plasma cells of IgG isotype in HG between the two groups(p>0.05).This indicates that CALT could promote the production of IgA、IgM in tears but had no significant effect on the production of IgG.

关 键 词：结膜相关淋巴组织 哈氏腺 点眼免疫 鸡 

分 类 号：S852.43[农业科学—基础兽医学]