安宫牛黄丸对重型颅脑损伤急性期血清镁离子的影响  

Effect of Angongniuhuang Pill on the Blood Magnesium Ion Concentration in the Acute Stage of Gravis Craniocerebral Injury

作　　者：袁淮涛[1] 黄良文[1] 项晓伟 胡鹏[1] 刘建仁[1] 戴先才[1] 朱文锐[1] 陈为[1] 刘建民[1] 

机构地区：[1]广东省广州中医药大学第一附属医院,广东广州510405 [2]广东省深圳市罗湖区中医院,广东深圳518000

出　　处：《中国中医急症》2013年第10期1650-1651,共2页Journal of Emergency in Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(81072907)

摘　　要：目的 观察安宫牛黄丸对重型颅脑损伤急性期患者外周血清镁离子的影响,从离子角度研究安宫牛黄丸对重型颅脑损伤急性期继发性损伤的防治作用.方法 将格拉斯哥昏迷（GCS）评分6～8分的颅脑损伤患者75例随机分为两组.对照组37例以常规方法治疗,治疗组38例在常规治疗基础上加用安宫牛黄丸,测定外周血清镁离子浓度、观察GCS评分变化并进行统计分析.结果 治疗第3、7、14日两组各项指标差异均有统计学意义（P＜ 0.05）.结论 在常规治疗的基础上加用安宫牛黄丸可提高重型颅脑损伤患者的外周血清镁离子浓度和GCS评分,从而减轻继发性脑损伤.Objective：To observe the effect of A ngongniuhuang Pill to the blood magnesium ion concentration in the acute stage of gravis craniocerebral injury and to study the effect of A ngongniuhuang Pill to treat and prevent the secondary cerebral injury.Methods：75 patients being diagnosed gravis craniocerebral injury（GCS6-8 points）were divided randomly into the control group with 37 patients and the experimental group with 38 patients.The control group was used the routine therapis and the experimental group was used above treatments plus the Angongniuhuang Pill.After treatment,these indices were observed such as the changes of the blood magnesium ion concentration and the GCS scores.Results：There were some obvious differences between 2 groups at the 3 th day,7 th day,14 th day.Conclusion：The Angongniuhuang Pill plus the western routine treatment can improve the blood magnesium ion concentration and the GCS scores.Then it can alleviate the secondary cerebral injury.

关 键 词：安宫牛黄丸 重型颅脑损伤 血清镁离子 继发性脑损伤 

分 类 号：R651.15[医药卫生—外科学]