护理干预对冠心病术后患者抑郁情绪和血清中P物质的影响  

The clinical observation on depression and substance P in coronary heart disease patients after operation by nursing intervention

作　　者：李雯[1] 杭国庆[2] 

机构地区：[1]浙江省丽水市人民医院麻醉科,浙江丽水323000 [2]浙江省慈溪市人民医院药剂科,浙江慈溪315300

出　　处：《中国现代医生》2013年第30期82-84,共3页China Modern Doctor

基　　金：浙江省医学会临床科研资金项目(2009ZYC18)

摘　　要：目的观察护理干预对冠心病术后患者抑郁评分与血清中P物质(substance P,SP)的影响,关注其表达的临床价值。方法选取260例冠心病术后患者,依入院顺序进行排序,并应用随机数字表的随机原则分为干预组(130例)和对照组(130例)。对照组患者实施专科护理常规,干预组在此基础上实施特定的护理干预,应用抑郁自评量表(SDS)评价两组的抑郁程度,应用ELISA检测两组干预前、干预后血清中SP的表达。结果干预组对抑郁评分的改善程度明显优于对照组,干预前两组血清中SP的表达无明显差别,干预后干预组SP的表达明显低于对照组。干预组对治疗的满意率明显高于对照组。结论护理干预对冠心病术后患者抑郁情绪有明显的改善作用,同时能有效地下调血清中与抑郁情绪进展相关的SP的表达,临床效果明显。Objective To investigate the depression scores and substance P（SP） expression in coronaly heart disease patients after operation by nursing intervention, analyze their clinical value. Methods A total of 260 post-operative cases with coronary heart disease were divided into observation group and control group with （130 cases） in each. The control group were applied by routine nursing methods, the observation group were applied by special nursing interven- tion. The depression scores were analyzed by SI）S Questionnaire. The SP expression was observed by ELISA. Results The s^ore change and satisfied rate were better in the observation group than in the control group. The expression of SP was lower in tile observation group than in the control group after intervention. Conclusion The specific nursing intervention can improve the depression emotion, decrease the expression of SP, is worthy to be applied in the elinieal work.

关 键 词：护理干预 术后患者 冠心病 后血清 P物质 抑郁情绪 ELISA检测 抑郁自评量表 

分 类 号：R473.5[医药卫生—护理学]