药物治疗顽固性高血压的研究进展  

Reseach progress in drugs used for resistance hypertension

作　　者：高翔[1] 

机构地区：[1]天津市红桥医院,天津300131

出　　处：《天津药学》2013年第5期61-64,共4页Tianjin Pharmacy

摘　　要：在高血压患者中,有15%～20%属于顽固性高血压。顽固性高血压具有更高的心血管事件的风险,给患者造成的危害也更严重。临床治疗顽固性高血压,需要结合患者的自身情况,选择不同的降压药联合用药。目前较为常用方案为血管紧张素转换酶抑制剂(或血管紧张素II受体阻滞剂)、钙拮抗剂和噻嗪类利尿剂3种药物组合,或由扩血管药、减慢心率药和利尿剂组合。本文综述了治疗顽固性高血压的联合用药方案和药物选择等方面的研究进展,为更好地治疗该病提供借鉴。In hypertensive patients, resistant hypertension accounted for about 15% - 20% . The risk of cardiovascular events in resistant hypertension is higher, the harm to patients caused by more serious. The clinical treatment of refractory hypertension, need to be combined with the patient＇s own situation, choose a different drug combination of antihypertensive drugs. At present the more commonly used for angiotensin converting enzyme inhibitors for angiotensin II receptor blockers} , calcium antagonists and thiazide diuretics 3 drugs, and composed of vasodilator, bradycardic and diuretic in 3 kinds of drugs. This paper reviewed the combination regimen, and treatment of resistant hypertension drug selection,and provide reference for better treatment of the disease.

关 键 词：顽固性高血压 临床治疗 联合用药 

分 类 号：R972.4[医药卫生—药品]