抗疲劳中药对小鼠抗疲劳作用的实验研究  

Anti-fatigue effect of herbs compound on mice: An experimental study

作　　者：麻懿馨[1] 范文今[1] 赵翠霞[1] 王晓丹[1] 谢韬[1] 

机构地区：[1]辽宁省疾病预防控制中心毒理检测所,辽宁沈阳110005

出　　处：《上海预防医学》2013年第10期592-594,共3页Shanghai Journal of Preventive Medicine

摘　　要：[目的]观察抗疲劳中药复方对小鼠抗疲劳作用的影响。[方法]以不同剂量(1.35、0.90、0.45 g/kg)抗疲劳中药复方给小鼠连续灌胃30 d,测定小鼠负重游泳时间,并检测小鼠肝糖原含量及运动疲劳小鼠血清尿素氮的含量。[结果]与对照组比较,抗疲劳中药复方能显著延长小鼠负重游泳时间,增加小鼠肝糖原含量,减少小鼠运动后血清尿素氮含量,且差异具有统计学意义(P<0.05)。[结论]抗疲劳中药复方对小鼠有明显的抗疲劳作用。[Objective] To observe the anti-fatigue effects of herbs compound in mice . [Methods] Different doses（1.35, 0.90, 0.45 g/kg） of herbs compound were given to mice for 30 days. In the study, the time of loaded-swimming, levels of glycogen in liver and serum urea nitrogen （BUN） were detected in the animals . [ Results] The time of swimming was significantly longer , the level of glycogen in liver higher but levels of serum BUN remarkably lower in the herbs compound group than those in the control （P〈0.05）. [Conclusion] The herbs compound has anti-fatigue effects on mice.

关 键 词：中药复方 抗疲劳 小鼠 负重游泳时间 肝糖原 尿素氮 

分 类 号：R285[医药卫生—中药学]