探讨迟发型狼疮肾炎35例临床与肾脏病理特点  

Discussion on the Clinical and Pathological Characteristics of 35 Cases of Late Onset Lupus Nephritis

作　　者：周生国[1] 李霞[1] 张伟[1] 吕莉娜 侯存 

机构地区：[1]山东省济宁市第一人民医院肾内科,山东济宁272000

出　　处：《中外医疗》2013年第26期13-14,共2页China & Foreign Medical Treatment

摘　　要：目的探讨分析迟发型狼疮肾炎(LOLN)患者的临床、肾脏病理特点。方法将年龄在50岁以上的LN(35例)患者作为此次研究的实验组,同期年龄在50以下的35例LN患者作为对照,分析患者的临床以及肾脏病理特点。结果两组患者肾脏病理类型比较,P>0.05;两组患者年龄、肾功能损害、肺间质病变比例、贫血、高血压、光敏感、面部红斑等情况比较,差异有统计学意义(P<0.05);实验组抗SSA阳性率高于对照组,P<0.05。结论 LOLN临床表现不典型,所以极易造成误诊,且年龄较大(年龄>50岁)的患者表现最为明显。Objective To analyze the clinical and pathological features of late onset lupus nephritis （LOLN）. Methods 35 LN pa- tients older than 50 years old were selected as the observation group, and 35 LN patients less than 50 years old during the same period were selected as the control group. The clinical and pathological characteristics of the groups were analyzed. Results There was no statistically significant difference in renal pathological types between the groups （P〉0.05）. There were statistically signifi- cant differences in age, renal function damage, interstitial lung disease, anemia, hypertension, the proportion of light sensitive and facial erythema between the groups（P〈0.05）. The anti-SSA positive rate of the experiment group was higher than that of the control group with statistically significant difference（P〈0.05）. Conclusion The clinical symptoms of LOLN are not typical, so it is very easy to be misdiagnosed. And patients older than 50 years old are the most easily to be misdiagnosed.

关 键 词：迟发型狼疮肾炎 肾脏病理特点 高年龄 

分 类 号：R692[医药卫生—泌尿科学]