穴位埋线联合中药及炔雌醇环丙孕酮综合疗法干预肾虚肝郁痰湿型多囊卵巢综合征临床观察  

Effect of Acupoint Catgut Embeding and Chinese medicine on menstruation in PCOS

作　　者：张迎春[1] 张花[1] 陈明[2] 李兰荣[1] 姜朵生[1] 李芳园[1] 

机构地区：[1]湖北省妇幼保健院中医科,湖北武汉430070 [2]湖北省武汉市中西医结合医院针灸科,湖北武汉430022

出　　处：《上海中医药杂志》2013年第10期34-37,共4页Shanghai Journal of Traditional Chinese Medicine

基　　金：湖北省妇幼保健院资助项目(220910021)

摘　　要：目的探讨穴位埋线联合中药及炔雌醇环丙孕酮(达英-35)综合疗法对多囊卵巢综合征肾虚肝郁痰湿型患者月经及排卵情况等的干预作用。方法将100例病例按随机数字表法分为治疗组与对照组,每组50例。两组均先口服西药炔雌醇环丙孕酮3个月,之后治疗组加用中药和穴位埋线法治疗;对照组加用氯米芬口服,并肌注促性腺激素(HMG)及人绒毛膜促性腺激素(HCG)治疗。两组疗程均为3个月,治疗前后检测血清内分泌激素促卵泡生成素(FSH)、黄体生成激素(LH)、睾酮(T)、雌二醇(E2)、泌乳素(PRL)水平,观察临床疗效,并随访停药3个月后的月经(周期、量)、优势卵泡生长数、排卵率、卵泡刺激综合征发生率。结果①治疗前后组内比较,治疗组LH、LH/FSH水平,对照组LH、LH/FSH、T水平差异均有统计学意义(P<0.05);停药3个月后两组月经情况及两组优势卵泡数、排卵率差异均有统计学意义(P<0.05)。②组间治疗后比较,LH、LH/FSH水平差异均有统计学意义(P<0.05),临床疗效差异有统计学意义(P<0.05);停药3个月后,月经情况、排卵率、卵泡刺激综合征发生率的差异均有统计学意义(P<0.05),优势卵泡生长数的差异无统计学意义(P>0.05)。结论穴位埋线联合中药及炔雌醇环丙孕酮综合疗法治疗多囊卵巢综合征能有效改善患者的月经情况,提高排卵率,下调LH、LH/FSH水平,且不易引起卵泡刺激综合征。Objective 300 explore the clinical efficacy about dyne-35 （compound cyproterone acetate） joint acupoint catgut embeding plus Chinese medicine which of treatment polycystic ovary syndrome. Methods After the system checks in line with the study of outpatients 100 cases by random number table, according to the treatment sequence randomly divided into treatment group （traditional Chinese medicine catgut embedding）, control group （the chlorine Mi Fenjia HMG ＋ HCG）. Both groups oral treatment for 3 months due t0-35, the treatment group with traditional Chinese medicine and the treatment of acupoint catgut embedding method; the control group with chlorine Mi Fen plus HMG ＋ HCG.. All observed objects observed before treatment and three months after treatment, serum sex hormones： FSH, LH, T, E2, PRL; number of bilateral ovarian follicles; observed six months after stopping menstruation （cycle, amount）, ovulation rate, and total efficiency, the data obtained using the SPSS 13.0 statistical analysis software statistics chemical treatment. Results Before and after treatment, there were signifcant differences in mustruation conditions between the two groups （ P 〈 O. 05 ）. There were significant differences in the levels of LH and LH/FSH of the treatment group, and significant differences were found in the LH level, LH/FSH level, T level and occurrence rate of dominant follicle in control group （ P 〈 O. 05 ）. Afler treatment, there were significant differences in mustruation condition, LH, LH/FSH, ovulation rate and occurrence rate of dominant follicle between the two groups （ P 〈 0.05 ）, and no significant difference was found in growth number of dominant follicle and comprehensive efficacy （ P 〉 0. 05 ）. Conclusion Acupoint catgut embedding method with traditional Chinese medicine treatment can effectively improve menstruation condition, ovulation rate, reduce the LH level and LH/FSH level, and are unlikely to cause follicle stimulating syndrome.

关 键 词：多囊卵巢综合征 穴位埋线 中药 炔雌醇环丙孕酮 

分 类 号：R711.75[医药卫生—妇产科学]