Housing characteristics and indoor environment in relation to children's asthma, allergic diseases and pneumonia in Urumqi, China  

作　　者：WANG TingTing ZHAO ZhuoHui YAO Hua WANG ShuLan NORBACK Dan CHEN Jie MA JinFeng JI XiaoLi WANG Li SUNDELL Jan 

机构地区：[1]Department of Maternal, Child and Adolescent Health, School of Public Health, Xinjiang Medical University [2]Department of Environmental Health, Key Laboratory of Public Health Safety, Ministry of Education, School of Public Health, Fudan University [3]The First Hospital Affiliated to Xinjiang Medical University [4]Center for Education Research [5]Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University [6]School of Management, Fudan University [7]Department of Building Science and Technology, Tsinghua University

出　　处：《Chinese Science Bulletin》2013年第34期4237-4244,共8页

基　　金：supported by the National Natural Science Foundation of China(30800894,71173045)

摘　　要：In order to evaluate the prevalence of childhood asthma,allergic diseases and pneumonia in Urumqi City,China,as well as its associations with housing and home characteristics,a cross-sectional study was performed in 4618 children(81.7%response rate,average age 4.7±0.9 year,boys accounting for 53.7%).Questions on children’s asthma and allergic diseases were from the International Study on Asthma and Allergies in Childhood(ISAAC)and were integrated with questions on the home environment from the Dampness in Buildings and Health(DBH)study,slightly modified to account for Chinese building characteristics and life habits.The prevalences of physician diagnosed asthma,allergic rhinitis(AR)and pneumonia were 3.6%,8.7%and 40.9%,respectively.One fourth of children reported wheezing and more than 40%AR symptoms in the last 12 months.Controlling for confounding factors,positive associations were found for home mold/dampness and wheezing(adjusted odds ratio,aOR 1.33,95%CI 1.07 1.66),AR symptoms(1.34,1.09 1.64)last 12 months and physician diagnosed pneumonia(1.33,1.09 1.62).Floor material by wood,PVC or carpeting;and walls by wallpaper,painting or wood material,were positively associated with AR symptoms.Home environmental tobacco smoke(ETS)was positively associated with wheezing(1.23,1.04 1.46)and pneumonia(1.25,1.07 1.45).In conclusion,there was a relatively high prevalence of asthmatic and AR symptoms and diagnosed pneumonia in preschool children in Urumqi.Home signs of mold growth or dampness,windowpane condensation,as well as ETS and interior surface materials emitting chemicals were risk factors for allergic symptoms and pneumonia.In order to evaluate the prevalence of childhood asthma, allergic diseases and pneumonia in Urumqi City, China, as well as its associations with housing and home characteristics, a cross-sectional study was performed in 4618 children （81.7% response rate, average age 4.7±0.9 year, boys accounting for 53.7%）. Questions on children＇s asthma and allergic diseases were from the International Study on Asthma and Allergies in Childhood （ISAAC） and were integrated with questions on the home environment from the Dampness in Buildings and Health （DBH） study, slightly modified to account for Chinese building characteristics and life habits. The prevalences of physician diagnosed asthma, allergic rhinitis （AR） and pneumonia were 3.6%, 8.7% and 40.9%, respectively. One fourth of children reported wheezing and more than 40% AR symptoms in the last 12 months. Controlling for confounding factors, positive associations were found for home mold/dampness and wheezing （adjusted odds ratio, aOR 1.33, 95% CI 1.07-1.66）, AR symptoms （1.34, 1.09-1.64） last 12 months and physician diagnosed pneumonia （1.33, 1.09-1.62）. Floor material by wood, PVC or carpeting; and walls by wallpaper, painting or wood material, were positively associated with AR symptoms. Home environmental tobacco smoke （ETS） was positively associated with wheezing （1.23, 1.04-1.46） and pneumonia （1.25, 1.07-1.45）. In conclusion, there was a relatively high prevalence of asthmatic and AR symptoms and diagnosed pneumonia in preschool children in Urumqi. Home signs of mold growth or dampness, windowpane condensation, as well as ETS and interior surface materials emitting chemicals were risk factors for allergic symptoms and pneumonia,

关 键 词：学龄前儿童 过敏性疾病 乌鲁木齐市 室内环境 肺炎 哮喘 中国 特征和 

分 类 号：R725.6[医药卫生—儿科]