燃煤型砷中毒患者的球结膜微循环改变  

Microcirculation Changes in Conjunctiva of Patients with Coal Arsenic Poisoning

作　　者：郭渝成[1] 张爱华[2] 张碧霞[1] 黄晓欣[1] 万功华[1] 杨大平[1] 董学新[1] 

机构地区：[1]解放军44医院,贵州省贵阳市550009 [2]贵阳医学院遗传毒理教研室

出　　处：《中国微循环》2000年第3期178-179,共2页Journal of Chinese Microcirculation

基　　金：受国家自然科学基金!39660070;贵州省自然科学基金!(3127)

摘　　要：探讨燃煤型砷中毒病人的微循环变化及其临床意义。方法应用LWB -Ⅰ型微循环仪对162例砷中毒病人及68例正常人作双眼球结膜微循环观测。结果不同程度砷中毒病人 ,其球结膜微循环变化也不尽相同。轻度砷中毒病人以球结膜微血管数目减少及血管周围渗出为主 ;中度砷中毒病人以血管粗细不均 ,血流速度缓慢较为显著 ;重度砷中毒病人的各项指标的异常发生率逐渐升高 ,尤以血球重度聚集及缺血区的出现更为突出。结论球结膜微循环障碍是慢性砷中毒病人的重要表现 ,监测其变化 ,有助于砷中毒病因的探讨。Objective To study the microcirculation changes of chronic coal arsenic poisoning patients and its clinical significance. Methods Observing both sides of conjunctiva microcirculation in 162 patients and 68 normals with LWB-Ⅰ microcirculation observing apparatus. Results There are different changes in different arsenic poisoning levels. Light arsenic poisoning is marked by deduction of microvascular and vascular exudate. Moderate poisoning causes microvascular to vary in diameter and bloodflow to slow down. Heavy poisoning is marked by serious aggregation of blood cells and emerging of ischemic area, together with many significant abnormal indicators. Conclusions Microcircular disorder in conjunctiva is one of the important indicators of chronic arsenic poisonong and measuring the changes is helpful not only for etiological research, but also for determination of patient's condition and treatment.

关 键 词：燃煤型砷中毒 微循环 球结膜 病理 治疗 

分 类 号：R599.902[医药卫生—内科学]