活血化瘀法防治二尖瓣球囊扩张术后再狭窄的疗效观察  

Evaluation on effect of activating blood and resolving stasis for mitral restenosis following percutaneous balloon mitral valvuloplasty

作　　者：夏晓健[1] 

机构地区：[1]江西省人民医院,南昌330006

出　　处：《江西医药》2013年第1期4-6,共3页Jiangxi Medical Journal

摘　　要：目的观察活血化瘀法防治经皮二尖瓣球囊扩张术(PBMV)后患者再狭窄的疗效。方法 100例患风湿性心脏瓣膜病二尖瓣狭窄患者,在我院行经皮二尖瓣球囊扩张术(PBMV)后,被分随机为活血化瘀治疗组和长效青霉素对照组。分别在二尖瓣球囊扩张术前、术后4-5d、术后6个月、12个月、3年等时间点通过超声心动图测量瓣口面积。结果随访6个月,两组患者二尖瓣瓣膜面积均有缩小的趋势,对照组更明显,但两者之间无显著差异(P>0.05)。随访12个月时,对照组瓣膜面积出现较明显缩小,与治疗组相比较差异存在统计学意义(P=0.48)。随访3年,对照组再狭窄9例,治疗组再狭窄2例,两组间存在显著差异。结论活血化瘀法防治二尖瓣球囊扩张术后再狭窄有良好的效果。Objective To assess effect of activating blood and resolving stasis for mitral restenosis in patients after percutaneous balloon mitral valvuloplasty（PBMV）.Methods Following PBMV,100 patients were randomized into activating blood and resolving stasis treatment group（n=50） and benzathine penicillin control group（n=50）,echocardiographic assessment was performed before and after the procedures,follow-up was performed in all patients for 3 years.Results A decline in mitral valve area was observed in both group at 6 months after PBMV howerver,there was no significant difference between two group（P 0.05）;at 12 months,the mitral valve area of treatment group decreased more slowly than that of control group（P=0.48）;at 3 years,there was more significant difference between two groups（P=0.24）;follow-up results of 3 years showed that there was significant difference between treatment group with 2 cases of restenosis and control group with 9 cases of restenosis（P0.05）.Conclusion Activating blood and resolving stasis can produce good clinical prevention mitral restenosis in patients after PBMV.

关 键 词：二尖瓣球囊扩张术 再狭窄 活血化瘀 

分 类 号：R542.51[医药卫生—心血管疾病]