慢性阻塞性肺疾病患者呼出气NO的检测及其临床意义  

Detection and clinical significance of exhaled nitric oxide in patients with chronic obstructive pulmonary disease

作　　者：魏蕾[1] 徐培军[1] 

机构地区：[1]淄博市中心医院,山东淄博255000

出　　处：《中国伤残医学》2013年第10期42-44,共3页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的:观察慢性阻塞性肺疾病(COPD)患者不同时期呼出气NO的变化及其临床意义。方法:应用尚沃纳库伦NO分析仪检测COPD患者急性发作期与稳定期呼出气中NO含量,并进行比较,并与健康人分别对比。结果:COPD患者稳定期呼出气NO含量明显低于健康人(P0.05),急性发作期患者呼出气NO含量明显高于健康人(P0.05)。结论:NO参与了COPD的病理生理过程,呼出气NO检测无创、方便,动态测定呼出气NO水平有助于对COPD病情的观察。Objective：To observe the changes of exhaled nitric oxide（ FeNO ） at different times in patients with chronic obstructive pul-monary disease（ COPD）, and investigate its clinical significance. Methods：FeNO levels were detected in remission of COPD, in acute epi- sode of COPD （AECOPD） , and in healthy people, by using Nano Coulomb nitric oxide Analyzer. Results ： The levels of remission of COPD were lower than healthy people, the levels of AECOPD were higher than healthy people. Conclusion： NO could participate in the patholog- ical and physiological process of COPD, detection of FeNO had non - invasive and convenient features , dynamic detection of FeON level should be helpful to assessing the state of COPD.

关 键 词：慢性阻塞性肺疾病 呼出气 NO 

分 类 号：R563[医药卫生—呼吸系统]