硫酸化酵母β-葡聚糖注射剂体内外抗菌活性及安全性研究  

Antibacterial effect and safety assessment of sulfated yeast β-glucan injection

作　　者：孙英峰[1] 池晶晶[1] 王东[1] 王英珍[1] 

机构地区：[1]天津市畜牧兽医研究所,天津300112

出　　处：《中兽医医药杂志》2013年第2期43-45,共3页Journal of Traditional Chinese Veterinary Medicine

基　　金：天津市应用基础及前沿研究计划面上项目(12JCYBJC20100)

摘　　要：对本实验室前期制备的兽用硫酸酯化酵母β-葡聚糖注射液进行安全性检验、体外抑菌和体内抗感染试验。结果表明,注射液体外对金黄色葡萄球菌有明显的抑制作用,但对溶血性链球菌、大肠埃希氏菌无抑制作用;体内抗感染作用显著,并具有较高安全性。Sulfated yeast β-glucan injection pre-prepared in our laboratory was studied to evaluate its safety and antibacterial effect in vitro and in vivo.The results showed that the injection had significant antibacterial activity against Staphylococcus aureus,and had no significant effect against hemolytic Strepto-coccus and Escherichia coli in vitro;It showed an significant anti-inflammatory effect and high safety in vivo.

关 键 词：硫酸化酵母β-葡聚糖注射剂 抗菌活性 安全性 

分 类 号：S853.74[农业科学—临床兽医学]