神经元移行异常MRI诊断  

MRI DIAGNOSIS OF ABNORMAL NEURONAL MIGRATION

作　　者：刘斋[1] 赵彦昭 何丽[1] 王伟秀[1] 任庆云[1] 

机构地区：[1]河北医科大学第一医院放射科,河北石家庄050031 [2]河北省晋州市人民医院CT室,河北晋州052260

出　　处：《河北医科大学学报》2013年第10期1150-1153,F0002,共5页Journal of Hebei Medical University

摘　　要：目的总结神经元移行异常的MRI特征,以提高对其MRI影像的认识。方法回顾性分析90例神经元移行异常患者的临床及MRI表现,总结MRI影像特征。结果 90例患者中,脑裂畸形18例,灰质异位32例,多微脑回畸形20例,巨脑回畸形15例,无脑回畸形3例,半侧巨脑症2例。脑裂畸形表现为大脑半球的横行裂隙,裂隙边缘衬有灰质信号。灰质异位表现为室管膜下及白质内结节状、团块状或带状病灶,在所有序列上都与正常脑灰质信号相同。多微脑回畸形表现为脑回增多、细小而浅,相邻蛛网膜下腔增宽。巨脑回畸形表现为脑回体积增大、皮质增厚、白质变薄。无脑回畸形表现为脑表面平滑,脑回脑沟消失,皮质增厚,白质变薄。半侧巨脑症表现为患侧大脑半球体积增大而对侧大脑半球体积缩小,患侧皮层发育不良。结论 MRI是诊断神经元移行异常的最佳影像学方法。Objective To summarize the features of neuron migration anomalies on MRI for the diagnosis and differential diagnosis.Methods Clinical data and MRI appearances of 90 cases with neuron migration anomalies were analyzed retrospectively.Results In 90 cases,there were schizencephaly 18 cases ; gray matter heterotopia 32 cases; polymicrogyria 20 cases; pachygyria 15 cases;agyria 3 cases;hemigiant brain 2 cases.Gray-matter-lined clefts which went through cerebral hemispheres from ventricle to hemispheric surface were characteristic imaging appearance of schizencephaly; gray matter heterotopia appeared as nodules,masses or bands located in white matter or periventricular regions,with identical signal intensities to the normal gray matter on all MRI sequences.In polymicrogyria,the volume of gyri decreased,but the number increased and the adjacent subarachnoid space widened.Pachygyria showed abnormally broad and flattened gyria with thickened cortical gray matter and reduce white matter.In agyria,the cerebral hemisphere was similar to the kidney in morphology,the surface of cerebral hemisphere was smooth,cortical sulci were shallow with thickened cortex and thin white matter.In hemimegalencephaly,the affected hemisphere was larger and the nonaffected side smaller in comparison with normal children.The most typical appearance showed the cortex to be dysplastic with broad gyri,shallow sulci,blurring of the cortical-white matter junction,and cortical thickening.Conclusion MRI is an important tool for the neuron migration anomalies.It can demonstrate the features of the disease,and improve the accuracy of the diagnosis.

关 键 词：脑疾病 神经元 磁共振成像 

分 类 号：R816.1[医药卫生—放射医学]