新生儿血型检测及抗体性质分析  

The analysis of neonatal blood group testing and character of antibody

作　　者：周金安[1] 何磊[1] 皮兰敢[2] 

机构地区：[1]华中科技大学同济医学院附属同济医院输血科,湖北武汉430030 [2]湖南省郴州市第一人民医院输血科,湖南郴州423000

出　　处：《国际检验医学杂志》2013年第20期2691-2692,共2页International Journal of Laboratory Medicine

摘　　要：目的统计新生儿血型正反定型一致的比例和抗体性质,分析抗体来源。方法用微柱凝胶卡的方法检测新生儿血型,正反定型一致的血清用二巯基乙醇(2-Me)破坏IgM类抗体,比较破坏前后抗体效价,确定抗体性质。结果 831例新生儿标本正反定型一致为477例,符合率为57.4%。利用2-Me破坏后抗体效价无变化的为93.9%,5.7%下降1倍,0.4%下降2倍。结论导致新生儿血型鉴定正反定型一致的抗体主要为IgG类。Objective Statistical analysis the proportion of consists of forward and reverse ABO typing in newborn,the properties and sources of antibodies were detected as well.Methods Microcolumn gelatin card methods were used to detect the blood types in newborn.2-Me was added to the serum for destructing the IgM class antibody.Then the antibody titers before and after destruction was compared,and the properties of antibody were determined.Results 831 samples of newborn were detected and 477 of them were consists of forward and reverse ABO typing,the coincidence rate was 57.4%.93.9% of antibody titers didn′t change,5.7% decreased by 1 time,0.4% fell 2 times.Conclusion IgG class anti-body is the main antibody which leads to consists of forward and reverse ABO typing in newborn.

关 键 词：血型 正反定型 符合率 抗体性质 

分 类 号：R446.6[医药卫生—诊断学]