复方苦参联合热疗治疗消化道肿瘤的疗效分析  

Curative Effect Analysis of Composite Radix Sophorae Flavescentis Combined with Thermotherapy on the Digestive Tumor

作　　者：韩新臣[1,2] 刘世育[1,2] 何晓华[1,2] 陈光侠[1,2] 

机构地区：[1]徐州市第一人民医院消化内科,江苏徐州221002 [2]徐州医学院附属市立医院内科学教研室

出　　处：《黑龙江医药》2013年第5期849-850,共2页Heilongjiang Medicine journal

摘　　要：目的:观察复方苦参联合体外高频热疗治疗晚期消化道肿瘤患者的临床疗效。方法:治疗组:采用体外高频热疗机进行局部肿瘤部位照射,隔日1次,1次60-120min,10次为一疗程,复方苦参注射液50 m1加入0.9%生理盐水250ml中静滴,1次/d,20d为一疗程。对照组:仅静滴复方苦参注射液,剂量、用法及疗程同治疗组。结果:①两组癌性疼痛疗效比较,治疗组完全缓解2例、明显缓解25例、轻度缓解10例、无效4例,有效率为65.8%;对照组有效率为40.0%,两组相比有统计学差异(P≤0.05)。②两组生存质量比较,治疗组显效7例、有效26例、无效8例,有效率为80.4%;对照组有效率为55.0%,两组有统计学差异(P≤0.05)。③两组体质量变化比较,治疗组体质量降低率低于对照组(P≤0.01)。结论:治疗组近期缓解率、生存质量及缓解癌痛均优于对照组,提示复方苦参注射液联合热疗较单纯应用复方苦参注射液能使较多患者临床受益。Objective To observe the curative effect analysis of composite radix sophorae flavescentis combined with thermotherapy on the digestive tumorous patients.Methods Therapy group：com- posite radix sophorae flavescentis 50ml with 0.9% saline , interve- nous drop infusion, one time every day, combined with out-of-body high-frequency thermotherapy one time every other day, continuous 20 days. Control group：only with composite radix sophorae flaves- centis,the dosage, usage and course of treatment are same to therapy group.Results （1）relieve pain of two groups comparison ：complete remission 2 cases, obvious remission 25 cases, partial remission 10 cases in 41 cases of therapy group, total effective rate is 65.8%; total effective rate of control group is 40.0%; There is statistics difference between two groups （P 〈 0.05）.（2）survival quality of two groups com- parison ： excellence 7 cases, utility 26 cases, ineffective 8 cases of therapy group, Ieffective rate is 80.4%, control group is 55.0%,there is statistics difference between two groups（P 〈 0.05）;（3） body weig）lt of two groups comparison： lower rate of therapy group is lower than control groups, （P 〈0.05）.Conelusions Remission rate, survival quality and relieve pain of therapy group all have an advantage to control group, to hint more patients profiting from the composite radix sophorae flavescentis combined with thermotherapy than simple ap- plication.

关 键 词：复方苦参 热疗 消化道肿瘤 疗效 

分 类 号：R979.1[医药卫生—药品]