烧伤新病房细菌流行病学调查  

Bacterial epidemioiogy in new burn wards

作　　者：刘赞[1] 周宇翔[1] 张丕红[1] 何亭[1] 张明华[1] 任利成[1] 梁鹏飞[1] 曾纪章[1] 黄晓元[1] 

机构地区：[1]中南大学湘雅医院烧伤重建外科,长沙410008

出　　处：《中华创伤杂志》2013年第10期928-930,共3页Chinese Journal of Trauma

摘　　要：目的了解烧伤科搬迁后新病房的病原菌分布及药敏变化。方法统计自2010年6月烧伤病房搬迁后送检各类标本中分离出来的菌株情况及药敏试验结果，分为2010年6月-2012年6月和2012年6月-2013年6月两个时间段，并与搬迁前2003年8月-2006年7月的住院患者细菌流行病学调查结果进行比较。结果2010年6月-2012年6月金黄色葡萄球菌检出率最高，铜绿假单胞菌与鲍曼不动杆菌分别位列第二、三位；而2012年6月-2013年6月鲍曼不动杆菌检出最多，铜绿假单胞菌和金黄色葡萄球菌位列其后，且铜绿假单胞菌、鲍曼不动杆菌与大肠埃希菌对亚胺培南和头孢他啶等多种抗生素的耐药性明显增强。结论烧伤病房多重耐药革兰阴性杆菌逐年增加，搬迁后前2年金黄色葡萄球菌检出增多、病原菌菌谱出现较大变迁可能与病房搬迁后环境改变、设备更新等有关。Objective To know the pathogenic bacteria distribution and drug susceptibility variation in the burns ward after the relocation. Methods Bacterial strains separated from all kinds of inspected samples and drug sensitive results were analyzed statistically since the removal of the burns ward in June 2010, including the time periods of June 2010-June 2012 and of June 2012-June 2013. Then a comparison was made with epidemiological results of bacteria involved in the patients hospitalized from August 2003 to July 2006 before the ward removal. Results From June 2010-June 2012, the detection ratio of staphylococcus anreus was the highest, followed by pseudomonas aernuginosa and acinetobacter baumannii; from June 2012-June 2013, acinetobacter baumannii was the most, followed by pseudomonas aeruginosa and staphylococcus aureus. In addition, the drug resistance of pseudomonas aeruginosa, acinetobacter baumannii and escherichia coli against antibiotics like imipenem and ceftazidime had been significantly enhanced. Conclusions There is a gradual growth of MDR gram-negative bacilli in burns u- nits each year, while the presence of staphylococcus aureus is increased in the first two years after the removal of burns ward. Significant variation of pathogen spectrum may be associated with the environmental changes and equipment renewal after the ward removal.

关 键 词：烧伤 细菌 流行病学 耐药性 

分 类 号：R446.5[医药卫生—诊断学]