高海拔地区肺间质性疾病合并肺纤维化的HRCT表现及其临床特点分析  

HRCT and clinical characteristics of interstitial lung disease with pulmonary fibrosis in high altitude region

作　　者：张志进[1] 张永海[1] 何晓芬[1] 张明[1] 胡海霞[1] 诺日嘉措 陈燕[1] 郑孝岭[1] 

机构地区：[1]青海省人民医院影像科,青海西宁810007

出　　处：《实用放射学杂志》2013年第10期1578-1581,1592,共5页Journal of Practical Radiology

摘　　要：从影像学角度探讨高海拔地区肺间质性疾病合并肺纤维化（PF-ILD）的高分辨率CT（HRCT）特征及其与病因、病程的关系。方法 对94例高海拔地区肺间质疾病中77例合并PF-ILD患者的HRCT特征、临床资料进行回顾性分析。结果 高海拔地区肺间质疾病的HRCT 表现为：小叶间隔增厚59例（76.6%）,小叶内间质增厚48例（62.3%）,支气管血管束异常31例（40.3%）,胸膜下弧线影29例（37.7%）,磨玻璃密度影20例（26.0%）,蜂窝征42例（54.5%）,网格状35例（45.5%）,支气管扩张29例（37.7%）,多发结节影6例（7.8%）,肺气肿56例（72.7%）,肺大泡22例（28.6%）。结论 高海拔地区PF-ILD发病率明显偏高（约81.9%）,病程长,合并症多,与高海拔缺氧及慢性高原疾病关系密切,HRCT检查具有重要的临床应用价值。Objective To explore the high-resolution CT （HRCT） characteristics of interstitial lung disease with pulmonary fibro sis （PF-II.D） in high altitude region, and the relationship among the image character, etiology and course of the disease. Methods HRCT features and clinical data of 77 patients who were detected PF ILD were retrospectively analyzed. Results HRCT characteristics of ILD in high altitude areas were as follows： interlohular septal thickening in 59 cases （76.6%）, lobular septal thickening in 48 patients （62.3%） , abnormality of bronchovascular bundles in 31 cases （40.3%） , subpleural line in 29 cases （37.7%） , ground glass opacity in 20 cases （26.0%） , Honeycomb sign in 42 cases （54.5%）, reticular opacities in 35 cases （45.5%）, bronchiectasis in 29 cases （37.7%）, muhiple nodules in 6 patients （7.8%） , emphysema in 56 cases （72.7%）, bullae in 22 cases （28.6%）. Conclusion The PF-ILD morbidity in high altitude was relatively high（about 81.9%）, with long course and many complications, which may be ch）sely related with high altitude hypoxia and chronic plateau diseases. HRCT play an important role in clinics of PF-ILD.

关 键 词：肺 高海拔地区 间质性肺疾病 计算机体层成像 

分 类 号：R563[医药卫生—呼吸系统] R563.13[医药卫生—内科学]