广州地区吸毒人员HBV、HCV感染流行病学特征  

HBV and HCV infection among drug addicts in Guangzhou

作　　者：熊华平[1] 花文峰[1] 王敏[1] 廖峭[1] 戎霞[1] 黄杰庭[1] 黄珂[1] 许茹[1] 付涌水[1] 

机构地区：[1]广州血液中心,广东广州510095

出　　处：《热带医学杂志》2013年第7期891-893,906,共4页Journal of Tropical Medicine

基　　金：广州市卫生局重点项目(201102A212010);广州市科技计划项目(2010UI-E00661);广州市卫生局一般引导项目(201102A213231)

摘　　要：目的了解广州地区吸毒人员乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)的感染状况及其影响因素。方法收集广州地区吸毒人员的血液标本,采用ELISA检测HBsAg及HCV抗体,并对吸毒人员采取统一调查表进行问卷调查,采用统计学方法进行相关性分析。结果 1375名吸毒者HBV、HCV的感染率分别为20.8%、39.2%,HBV/HCV合并感染率为7.7%(106/1375)。其中采用静脉吸毒者HBV、HCV的感染率分别24.5%、84.5%,均高于非静脉吸毒者的19.2%、19.8%,差异有统计学意义(P<0.05)。吸毒者年龄越大、吸毒时间越长越容易发生HBV或HCV感染。结论吸毒尤其是静脉吸毒是HBV、HCV感染的高危因素。吸毒者年龄、吸毒时间长短及吸毒方式与HBV、HCV感染相关。Objective To investigate the infection rates and the impact of HBV and HCV infection among drug addicts in Guangzhou. Methods Questionnaire survey was conducted in this study. Blood samples from the drug addicts were collected. HBsAg and HCV antibodies were detected by ELISA assays. The correlation between infection and possible impact factors were analyzed by SPSS16.0 software. Results Of the 1 375 drug addicts, the percentage of HBV and HCV infection was 20.8% and 39.2%, respectively. 106 cases （7.7%） were found to have HBV and HCV co-infection. 412 cases were intravenous drug users （IDUs）,in which the HBV and HCV infection rate was 24.5% and 84.5%, respectively. Elderly and those with a long history of drug addiction had a higher risk of having HBV and HCV infection. Conclusions Drug addiction, especially through the intravenous injection, is the risk factor of HBV and HCV infection. Age, the history of drug addiction, and intravenous drug injection are correlated with HBV and HCV infection.

关 键 词：乙型肝炎病毒 丙型肝炎病毒 静脉吸毒 

分 类 号：R512.6[医药卫生—内科学]