广州市无偿献血者梅毒阳性分布情况  

Seroprevalence of syphilis positive among blood donors in Guangzhou from 2008 to 2012

作　　者：徐国胜[1] 杨穗群[1] 林昌周[1] 刘杏[1] 李晓帆[1] 

机构地区：[1]广州血液中心,广东广州510095

出　　处：《热带医学杂志》2013年第8期1032-1034,共3页Journal of Tropical Medicine

摘　　要：目的对近年广州市无偿献血者的梅毒感染情况进行流行病学调查,为降低经输血传播梅毒的风险提供理论依据。方法对2008-2012年广州市无偿献血者1337287份血标本采用ELISA双抗原夹心法进行梅毒抗体初筛检测,初筛阳性标本采用TPPA方法进行确认。结果 2008-2012年广州市1337287份无偿献血者标本中,检出梅毒抗体阳性5355份,阳性率为0.40%。2008-2012年各年份阳性率分别为0.43%、0.37%、0.43%、0.38%、0.39%,无偿献血人群梅毒抗体阳性率总体呈下降趋势。其中,男性阳性率高于女性;18～30年龄段献血员梅毒阳性率明显低于31～55岁年龄段人群,阳性率随着年龄的增长而上升;高学历献血员阳性率低于低学历献血员;农民和自由职业献血员梅毒阳性率最高,学生和医务人员梅毒阳性率最低。结论无偿献血者中,梅毒抗体阳性人群在性别、年龄、学历、职业上的分布差异均有统计学意义,从低危人群中招蓦无偿献血者,并重点针对高危人群宣传梅毒防治知识,是降低输血传播梅毒风险的重要措施。Objective This study was undertaken with the aim of determining the seroprevalence of syphilis among blood donors in Guangzhou city,in order to avoid the syphilis infection through blood donation.Methods 1 337 287 sera samples from blood donors were screened for Treponema pallidum antibody,using enzyme linked immunosorbent assays （ELISA）.All the positive samples were confirmed with TPPA test.Results From the total of 1 337 287 blood donors,5 355 （0.40%） were positive for syphilis.From 2008 to 2012,the positive rates were 0.43%,0.37%,0.43%,0.38% and 0.39%,respectively,which was reduced year by year.About gender distribution,the positive rate of male was higher than that of female.About age distribution,the positive rate in the age group of 18-30 years old was lower than that of 3155 years old.About the education distribution,the positive rate of the groups with higher education level was lower than that of the lower educated level.About the occupation distribution,the positive rate of farmers and free occupation was the highest,and of students and doctors was the lowest.Conclusions The seroprevalence of syphilis showed significant differences in age,gender,occupation and education level.Strict selection and recruitment of low-risk blood donors are recommended to improve blood safety in the blood transfusion.

关 键 词：无偿献血者 梅毒 阳性 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]