地佐辛在术后恢复室中镇静镇痛效果的临床观察  

The sedative and analgesia effect of dezocine on patients in recovery room

作　　者：汪一梦[1] 万杏[1] 孟庆涛[1] 

机构地区：[1]武汉大学人民医院麻醉科,湖北武汉430060

出　　处：《热带医学杂志》2013年第9期1122-1123,共2页Journal of Tropical Medicine

摘　　要：目的观察地佐辛在术后恢复室中镇静镇痛的效果。方法选择全身麻醉手术术后患者90例,随机分为地佐辛(D组)、芬太尼组(F组)和咪唑安定组(M组),D组给予0.1 mg/kg地佐辛,F组给予1μg/kg芬太尼,M组给予0.02 mg/kg咪唑安定。观察镇静和躁动评分(SAS)、疼痛视觉模拟评分(VAS)、布氏舒适评分(BCS)及不良反应等指标。结果与M组比较,D组、F组可以明显降低SAS、VAS评分,增加BCS评分,差异有统计学意义(P<0.01),而D组与F组之间相比差异无统计学意义(P>0.05)。D组患者的呼吸抑制、嗜睡、恶心呕吐发生率明显低于F组,差异有统计学意义(P<0.05)。结论地佐辛用于术后恢复室患者镇静镇痛效果确切,且呼吸抑制发生率低,具有良好的临床应用前景。Objective To evaluate the sedative and analgesia effect of dezocine on patients in recovery room. Methods 90 adult patients were randomly divided into three groups： dezoeine group （D）, fentanyl group （F） and midazolam group （M）. O. 1 mg/kg of dezocine, 1 bLg/kg fentanyl, 0.02 mg/kg midazolam was given to group D, group F, and group M, respectively. The scores of SAS, VAS, BCS and the number of respiratory depression were recorded. Results There was a significant difference in the values of SAS, VAS, and BCS scores when group D and group F were compared with group M. There was also a significant difference in the number of respiratory depression when group F was compared with group D and group M. Conclusion The sedative and analgesia effect of dezocine is suitable for patients in the recovery room. The occurrence of respiratory depression is also lower in patients.

关 键 词：地佐辛 术后恢复室 镇静 镇痛 

分 类 号：R452[医药卫生—治疗学] R453[医药卫生—临床医学]