医药行业蒸馏系统蒸气云爆炸模型的研究  

The vapor cloud explosion model research in pharmaceutical industry distillation system

作　　者：王奔[1] 张俪昽[2] 丁峰[3] 丁旭东[2] 赵保成 宋文华[2] 

机构地区：[1]湖南省公安消防总队株洲市消防支队防火处,湖南株洲412011 [2]天津工业大学环境与化学工程学院,天津300387 [3]天津市测绘院,天津300381 [4]天津太平洋化学制药有限公司,天津300350

出　　处：《中国安全生产科学技术》2013年第9期137-141,共5页Journal of Safety Science and Technology

基　　金：天津市科技支撑计划重点项目(13ZCZDSF02000)

摘　　要：医药行业对药品生产的纯度控制相当重要,蒸馏操作是医药行业普遍运用的工艺手段之一。但由于蒸馏工序所涉及的物料常伴随具有较强燃爆性的危险化学品,且闪点以上操作加剧了物料的燃爆危险,因此医药行业蒸馏系统便成了事故多发的工艺单元之一。通过对某公司蒸馏系统的危险性分析,找出了蒸馏系统存在燃爆危险的主要因素,再进一步采用蒸汽云爆炸事故模拟评价方法,结合拉乌尔定律和道尔顿分压定律对该公司蒸馏系统进行安全评价,确定蒸馏系统二元混合物蒸气云爆炸冲击波损害半径。The purity of pharmaceutical production to is quite important for pharmaceutical industry. Distillation operation is one of the widely applied means in pharmaceutical industry. But the distillation operation is one of the units which are easy to have the accidents, just because the materials of the distillation process often involve dan- gerous chemicals with strong combustibility and explosiveness, and the operation is above the flash point. This arti- cle try to find the main factors of the combustion hazards in distillation system based on a certain company＇ s distil- lation system. And then do the safety evaluation by using the vapor cloud explosion accident simulation evaluation method, Raoult~ law and Dalton~ law of partial pressures. Determine the vapor cloud explosion wave damage radi- us, and amend the calculated results.

关 键 词：蒸馏系统 二元混合物 危险性分析 蒸气云爆炸事故模拟 损伤半径 

分 类 号：X932[环境科学与工程—安全科学]