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作 者:崔燕海[1] 黄美萍[1] 刘辉[1] 杨向太[1]
机构地区:[1]广东省人民医院暨广东省医学科学院放射科,广东广州510080
出 处:《医学影像学杂志》2013年第10期1550-1552,共3页Journal of Medical Imaging
基 金:广东省科技计划项目(2010B031600172);广东省科技计划项目(2011B031800045)
摘 要:目的通过比较心功能不全患者与正常对照组肺循环灌注情况,探讨MRI肺循环灌注成像的临床应用价值。方法分别对15例正常对照者和21例心功能不全患者行对比剂增强的MRI灌注成像,采用两个独立样本t检验分别对两组间肺循环相关灌注参数进行统计学比较。结果正常对照组和心功能不全组分别的右室达峰时间为(5.81±2.30)s和(8.91±4.34)s、肺实质达峰时间为(7.12±2.07)s和(12.67±5.29)s、左室达峰时间为(7.75±2.17)s和(14.85±5.94)s、右室-肺实质峰值间隔时间为(3.16±1.79)s和(6.25±3.60)s、肺实质-左室峰值间隔时间为(3.10±1.30)s和(5.34±3.39)s、右室-左室峰值间隔时间为(6.26±1.79)s和(11.59±3.59)s,两组间的各参数的差异均具有统计学意义。结论对比增强MRI灌注成像能够反映不同心功能状态下肺循环参数的情况,具有进一步临床应用研究的价值。Objective To assess the feasibility and value of quantitative analysis of pulmonary perfusion using contrast enhancement magnetic resonance imaging (CE-MRI) through the comparison of patients with cardiac dysfunction and controls. Methods 21 patients with cardiac dysfunction (Group A) and 15 controls without cardiac dysfunction (Group B) underwent pulmonary perfusion CE-MRI. Quantitative perfusion analysis was performed using novel software to assess pulmonary circulation parameters. Two independent samples t-test was used for statistics analysis. Results The time to peak of right ventricle (pTRV), time to pulmonary parenchyma (pTPP), time to left ventricle (pTLV), interval time of pTRV and pTPP(TRV-PP), interval time of pTPP and pTLV(TPP-LV) and interval time of pTRV and pTLV(TRV- LV) were respectively (8.91±4.34) s, (12. 67±5. 29) s, (14.85±5.94) s, (6.25±3.60) s, (5. 34±3. 39) s and (11.59±3.59) s in group A. And those were (5.81±2.30) s, (7. 12±2.07) s, (7.75 ± 2. 17) s, (3.16±1.79) s, (3.10±1.30) s and (6.26±1.79) s in group B. There was significant difference between two groups. Conclusion Quantitative pulmonary perfusion using CE-MRI could demonstrate the changes of pulmonary circulation with the difference of cardiac function, which is worth of researching deeply.
分 类 号:R54[医药卫生—心血管疾病] R445.2[医药卫生—内科学]
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