尿道吊带置入治疗神经源性尿失禁的研究与应用  

Research and application of urethral sling placement on neurogenic incontinence

作　　者：丁留成[1] 黄懿[1] 卫中庆[1] 

机构地区：[1]南京医科大学第二附属医院,江苏省南京市210000

出　　处：《中国组织工程研究》2013年第44期7791-7796,共6页Chinese Journal of Tissue Engineering Research

基　　金：国家自然科学基金(81300572);江苏省自然科学基金(SBK201123829)~~

摘　　要：背景:采用适当的材料、合理的吊带置入方式置入体内,可以达到恢复神经源性尿失禁患者储尿的目的,而吊带材料的选择以及安全有效的张力控制至关重要。目的:文章综述了不同材料治疗压力性尿失禁的方法、疗效及安全性等方面的研究进展。方法:应用计算机检索1986年1月至2012年1月PubMed数据、英文数据库、CNKI数据库及查阅相关英文书籍,收集与尿道吊带材料、尿道吊带置入方式、疗效及安全性等相关文献。英文检索词包括"urethral sling,neurogenic,urinary incontinence";中文检索词包括"尿道吊带;神经性;尿失禁"。根据纳入排除标准,最终选择47篇文章进行综述。结果与结论:采用自体筋膜或各种合成材料作为尿道吊带置入体内,具有安全、简便、微创等优点。神经源性尿失禁机制主要与膀胱功能的改变或尿道括约肌功能不全有关,由于病情复杂,保证此类患者置入后的储尿和控尿能力依旧是一大难题。BACKGROUND： The patients with neurogenic urinary incontinence could be cured to restore their urinary storage function through the implant of the suburethral sling made of appropriate materials in a reasonable way. Meanwhile the choice of materials and the safe and effective control of tension are crucial factors. OBJECTIVE： To review the implanted methods, effectiveness and safety of sling made of different materials in the surgical treatment of neurogenic stress urinary incontinence. METHODS： The PubMed database, English database, CNKI database and related English books were retrieved with computer from January 1986 to January 2012 for the articles on the urethral sling material, urethral sling placement methods, efficacy and safety. The key words were ＂urethral sling, neurogenic, urinary incontinence＂ in English and Chinese. Finally, 47 articles were included for review according to the inclusion and exclusion criteria RESULTS AND CONCLUSION： Urethral sling is a safe, handy, and micro-invasive operation, by using autologous fascia or various synthetic materials to implant into the body. The mechanism of neurogenic urinary incontinence is mainly related with the change of bladder function or the insufficiency of urethral sphincter function. However, it is still a big problem for us to assure the postoperative ability of such patients to store and control urine because of their complicated conditions.

关 键 词：器官移植 器官移植综述 尿道吊带 神经性 尿失禁 神经源性尿失禁 尿动力学 膀胱颈筋膜吊带术 自体筋膜 国家自然科学基金 

分 类 号：R318[医药卫生—生物医学工程]