肾移植后并发糖尿病的危险因素及治疗  

Risk factors and treatment for diabetes mellitus after kidney transplantation

作　　者：孙艳浮 李蒙[2] 李瑞玉[1] 吴立萍[3] 

机构地区：[1]邢台医学高等专科学校第二附属医院中西医结合研究所,河北省邢台市054000 [2]武警新疆总队和田地区支队卫生队,新疆维吾尔自治区和田市848011 [3]河北医科大学附属邢台市人民医院检验科,河北省邢台市054031

出　　处：《中国组织工程研究》2013年第44期7803-7808,共6页Chinese Journal of Tissue Engineering Research

基　　金：河北省中医药管理局资助项目(2012068)~~

摘　　要：背景:肾移植后并发糖尿病是肾移植治疗后常见的并发症之一。目的:探讨肾移植后并发糖尿病的危险因素以及临床治疗。方法:应用数据库文献检索的方法获取肾移植后并发糖尿病研究的文献,对符合研究标准的文献进行深入的数据分析,文章选取肾移植后并发糖尿病的危险因素进行深入分析,并总结国内外关于肾移植后并发糖尿病的治疗方法。结果与结论:肾移植后并发糖尿病是由多种因素作用而引起的糖代谢异常,肾移植后并发糖尿病与患者年龄、体质量指数、血脂水平、免疫抑制剂方案、急性排斥发生频率、糖皮质激素累积等因素相关。在肾移植后定期检测血糖变化,可以较早的发现糖尿病的发生,通过中西医药物降低血糖和调整免疫抑制剂等方法可以有效治疗。BACKGROUND： Diabetes mellitus is a common complication after kidney transplantation. OBJECTIVE： To investigate the risk factors for diabetes mellitus after kidney transplantation diabetes mellitus risk factors and clinical treatment based on integrative medicine. METHODS： Literatures concerning diabetes mellitus after kidney transplantation were retrieved in the database, and the articles that met the study criteria were analyzed. In this paper, we analyzed the risk factors for diabetes mellitus and concluded the therapies for diabetes mellitus after kidney transplantation. RESULTS AND CONCLUSION： Diabetes meUitus after kidney transplantation is an abnormal glucose metabolism caused by multiple factors, which is related to age, body mass index, lipid levels, immunosuppressantprogram, frequency of acute rejections, and cumulative dose of glucocorticoid. Periodic monitoring of blood glucose after kidney transplantation contributes to the earlier detection of the occurrence of diabetes mellitus. Integrative medicines that can lower blood glucose level and immunosuppressant adjustment can be effective for the treatment of diabetes mellitus after kidney transplantation.

关 键 词：器官移植 器官移植学术探讨 肾移植 糖尿病 危险因素 免疫抑制剂 糖皮质激素 环孢素A 他克莫 司 治疗 预防 省级基金 

分 类 号：R318[医药卫生—生物医学工程]