^(18)F-FDG PET/CT显像对食管癌的诊断价值  

Diagnostic value of ^(18)F-FDG PET /CT for esophageal cancer

作　　者：谢红军[1] 宋文忠[1] 刘浩[1] 刘兆辉[1] 

机构地区：[1]四川省医学科学院.四川省人民医院核医学科,四川成都610072

出　　处：《实用医院临床杂志》2013年第6期35-37,共3页Practical Journal of Clinical Medicine

摘　　要：目的探讨FDG PET/CT显像对食管癌的诊断价值。方法 45例临床初诊食管癌患者行全身PET/CT显像,以最大SUV值(SUVmax)>2.5为PET阳性,局限性食管壁增厚伴管腔狭窄为CT阳性。以病理为最终判断标准。结果病理证实40例食管癌,39例PET/CT为阳性,1例阴性;5例食管慢性炎症,2例阳性,3例阴性。45例患者中,PET/CT阳性41例,阳性率为91.1%,敏感性97.5%(39/40),特异性60%(3/5),准确性93%(42/45)。28例淋巴转移,PET/CT阳性25例,3例阴性,敏感性为82.1%,特异性83.3%;双时相显像30/40食管癌患者SUV值增加,食管炎SUV值变化不明显。结论 PET/CT对食管癌诊断准确率高,对有无淋巴结转移也有较高的准确性;但病灶仅限于黏膜患者,PET/CT可出现漏诊。Objective To investigate the diagnostic value of ^18 F-fluorodeoxyglucose （FDG）PET/CT for esophageal cancer. Methods Forty-five cases with esophageal cancer diagnosed by clinical visit were examined with 18F-FDG PET/CT. Lesions were defined as positive if the maximum standardized uptake value（SUVmax） 〉2. 5 in PET and local wall thickening or lumina stenosis in CT. The results were compared with pathological examinations. Results In the 45 cases ,40 cases were confirmed as esophageal cancer by pathological examination while 39 cases were found positive in PET/CT. For five cases with esophagitis,2 cases were found positive and 3 negative. Thus, sensitivity, specificity and accuracy of the method were 97. 5 % （39/40） ,60 % （ 3/5 ） and 93 % （42/45）, respec- tively. For 28 cases with lymphatic metastasis,25 cases were positive and 3 cases were negative. Therefore, sensitivity and specificity for metastasis were 82. 1% and 83.3% ,respectively. In the delayed imaging,30 cases with esophageal cancer showed an increased SUV-max while no change was found in patients with esophageal inflammation. Conclusion PET/CT is an accurately diagnostic tool for e-sophageal cancer as well as lymphatic staging. However,it may be missed if a lesion is restricted at membrane.

关 键 词：食管肿瘤 肿瘤转移 发射型计算机 体层摄影术 X射线计算机 脱氧葡萄糖 

分 类 号：R816.5[医药卫生—放射医学] R735.1[医药卫生—临床医学]