2001～2010年四川省围产儿出生缺陷监测分析  

Monitoring analysis of birth defects in Sichuan province from 2001 to 2010

作　　者：刘敬涛[1] 许跃忠[1] 何琳坤[1] 陈琴[1] 吴方银[1] 

机构地区：[1]四川省妇幼保健院妇幼信息管理科,四川成都610045

出　　处：《实用医院临床杂志》2013年第6期63-65,共3页Practical Journal of Clinical Medicine

基　　金：四川省卫生厅科研课题基金资助(编号:090398)

摘　　要：目的了解四川省围产儿出生缺陷发生状况,更好落实干预措施。方法按照国家出生缺陷监测方案,以医院为基础的出生缺陷监测方法收集资料。结果 2001～2010年四川省围产儿出生缺陷总发生率为130.18/万,10年间呈上升趋势。前五位出生缺陷病种占全部缺陷类型的47.63%,依次为外耳及其他畸形22.41/万,多指(趾)14.11/万,总唇裂12.98/万以上,先天性心脏病8.81/万,小耳5.86/万。出生缺陷发生率城镇高于农村,男婴高于女婴,产妇年龄≥35岁的出生缺陷发生率明显高于其余年龄段产妇所生的围产儿。结论 2001～2010年四川省围产儿出生缺陷发生率处较高水平,提示应针对危险因素确定出生缺陷干预工作重点,对高发的外耳及其他畸形进行必要的病因学和人群分布等方面研究,为降低出生缺陷发生率提供依据。Objective To investigate the incidence of birth defects among perinatal infants and the main influencing factors in Sichuan province. Methods According to national birth defect monitoring program, the data was collected with hospital-based birth defects monitoring method. Results The prevalence of birth defects was 130. 18 per ten thousand from 2001 to 2010 in Sichuan prov-ince, and showed a rising trend. The top five diseases of deformities were external ear and other malformation（22. 41 per ten thousand） , polydactyly （ 14. 11 per ten thousand）, cleft lip with or without Cleft Palate （ 12. 98 per ten thousand）, congenital heart disease （8.81 per ten thousand） and microtia（5.86 per ten thousand）. The first five birth defects accounted for 47.23 percent of all types of defects. The prevalence of birth defects in urban areas was significantly higher than that in rural areas. Birth defects rate in boys was significantly higher than that in girls. The prevalence of birth defects in group of maternal age ≥ 35 years old was the highest, and significantly high-er than that in other age groups. Conclusion The prevalence of perinatal birth defects was high in Sichuan province. We should deter- mine the birth defect intervention according to the risk factors, and study the etiology and the population distribution for external ear and other malformation,which would provide evidence for reducing the prevalence of birth defects.

关 键 词：出生缺陷 围产儿 监测 

分 类 号：R714.7[医药卫生—妇产科学]