降钙素原对儿童脓毒症早期诊断的临床意义  

Clinical significance of procalcitonin in early diagnosis of children with sepsis

作　　者：李运璧[1] 彭茜[1] 朱小石[1] 李建超[1] 陈丽娜[1] 邓俊超[1] 

机构地区：[1]四川省医学科学院.四川省人民医院儿科,四川成都610072

出　　处：《实用医院临床杂志》2013年第6期163-164,共2页Practical Journal of Clinical Medicine

摘　　要：目的评价降钙素原(proealcitonin,PCT)对儿童脓毒症早期诊断的临床应用价值。方法选择同期住院符合入选条件的脓毒症患儿62例(脓毒症组)和非脓毒症患儿48例(非脓毒症组),比较两组间PCT、CRP水平。结果脓毒症组PCT显著高于非脓毒症组,差异有统计学意义(P<0.05)。PCT的敏感性、特异性高于CRP,差异有统计学意义(P<0.05)。结论 PCT对儿童脓毒血症的早期诊断、判断病情及治疗效果的评估,具有一定的临床应用价值。Objective To evaluate the clinical application value of procalcitonin （PCT） in early diagnosis of children with sepsis. Methods Sixty-two children with sepsis （ septic group） and 48 cases without sepsis （non-septic group） were chosen in hospi- tal at the same time. The levels of PCT and C-reactive protein （CRP） were compared between the two groups. Results The levels of PCT and CRP in the septic group were significantly higher than that in the non-sepsis group （P 〈0. 05）. Moreover, sensitivity and spe-cificity of PCT were higher than that of CRP. Conclusion It has certain clinical application value of PCT in children with sepsis in early diagnosis, prognosis, and assessment of treatment efficacy.

关 键 词：降钙素原 脓毒血症 儿童 

分 类 号：R725[医药卫生—儿科]