体检职工血压水平与血清尿酸水平的关系  

Relationship between blood pressure level and serum uric acid level of workers undergoing physical examination

作　　者：钱德富[1] 郭勤[1] 任慧[1] 范敬东[1] 冯驰[1] 朱谱国[1] 周子华[2] 廖玉华[2] 

机构地区：[1]中国航天三江集团湖北航天医院心内科,湖北孝感432000 [2]华中科技大学同济医学院附属协和医院

出　　处：《公共卫生与预防医学》2013年第5期57-60,共4页Journal of Public Health and Preventive Medicine

摘　　要：目的了解2010年3月至2011年9月某单位体检职工血压水平与UA水平的相互关系。方法安排在职职工和离退休职工21 700人(不含家属)体检,实际体检16 416人,符合研究要求且资料完整者14 041人。体检内容包含体格检查和实验室检查,缺乏药物使用情况资料。采用专用体检记录电脑软件录入体检者资料,体检结束后导出数据,用SPSS分析软件分析血压水平与UA水平的关系。结果体检职工达高血压水平者占35.76%,HUA为11.19%。血压水平越高UA水平越高、HUA比例越高,组间差异有统计学意义(P<0.05)。体检职工血压水平达高血压者的UA均值、HUA比例>非高血压者,差异有统计学意义(P>0.05)。HUA者SBP、DBP均值>非HUA者。相关分析显示体检职工UA水平与年龄、SBP、DBP、BMI、FPG、TC、TG、LDL-C正相关,与HDL-C、性别负相关,差异有统计学意义(P<0.05)。多元回归方程中SBP、BMI、FPG、TG、LDL-C、HDL-C、性别差异有统计学意义(P<0.05),年龄、DBP、TC差异无统计学意义(P>0.05);女性与年龄、DBP差异有统计学意义(P<0.05),男性则无关;男性UA水平与LDL-C差异有统计学意义(P<0.05),女性差异无统计学意义(P>0.05)。结论体检职工血压水平越高UA水平越高,高血压者的UA水平、HUA比例>非高血压者。HUA者的血压水平>非HUA者。Objective To investigate the relationship between the blood pressure level and uric acid level of the workers undergoing physical examination in a unit from March 2010 to September 2011. Methods 21 700 workers and retirees （excluded family relatives） were arranged for physical examination. 16 416 were actually examined. 14 041 met research requirements with complete data. Clinical examination and laboratory examination, （medication not included ） were performed. By the aid of specific physical examination record software, all the records of the physical examination were obtained. The relationship between blood pressure level and UA level were analyzed by SPSS Software. Results Among the physical examination population, the cases of high blood pressure were 35.76%, and those of HUA, 11.19%. The higher the blood pressure level, the higher the UA level and the HUA rate, and the difference between different groups was of statistic significance. The UA mean and the HUA rate of high blood pressure in the examined workers were more than that of non high blood pressure cases. The SBP and DBP mean values of HUA cases were higher than those of non-HUA cases. The correlation analysis indicated that UA level had positive correlation with age, SBP, DBP, BMI, FPG, TC, TG, LDL-C, and negatively correlated with HDL-C, gender. The difference was of statistic significance. There was statistic significance difference in SBP,BMI,FPG,TG,LDL-C,HDL-C,gender in multiple regression equation, while no difference in age,DBP and TC. Women, age and DBP had statistical significance, while no statistical difference in men; UA level and LDL-C had statistical significance in men, while no statistical difference in women. Conclusions The higher the blood pressure level,the higher the UA level and the HUA rate. The UA level and the HUA prevalence rate of the cases of high blood pressure were higher than those of the cases of normal blood pressure. Blood pressure level of HUA cases was higher than that of non- HUA cases.

关 键 词：血压 血清尿酸 患病率 危险因素 

分 类 号：R544[医药卫生—心血管疾病]