北京市2013年新发现D8基因型麻疹病例的流行病学调查  

Investigation on measles cases of new genotype D8 in Beijing, 2013

作　　者：李娟[1] 卢莉[1] 马蕊[1] 陈萌[1] 李爱华[1] 孙穆[2] 史淑芬[2] 卢渝军 王中占[3] 毛雯雯[3] 富继业[4] 马天薇[4] 王海红[5] 随海田[5] 赵立平[6] 解艳涛[6] 黄芳[1] 吴疆[1] 庞星火[1] 

机构地区：[1]北京市疾病预防控制中心,100013 [2]北京市西城区疾病预防控制中心计划免疫科 [3]北京市丰台区疾病预防控制中心预防免疫科 [4]北京市海淀区疾病预防控制中心计划免疫科 [5]北京市昌平区疾病预防控制中心计划免疫科 [6]北京市通州区疾病预防控制中心计划免疫科

出　　处：《中华流行病学杂志》2013年第11期1111-1114,共4页Chinese Journal of Epidemiology

摘　　要：目的 调查2013年1-6月北京市新发现D8基因型麻疹病例的流行病学特征.方法 开展现场流行病学调查,采用描述流行病学方法进行分析.结果 2013年1-6月北京市共报告疑似麻疹病例661例,经血清学和病原学检测确诊麻疹病例416例,经基因型鉴定发现D8基因型28例,其中14例病例分属于2起暴发疫情,14例为散发病例.暴发疫情和散发病例发病高峰均在4-5月,分布城区和近郊区25例（89.3％）,15～39岁成年人22例（78.5％）,外省户籍人口19例（67.9％）.暴发疫情病例中有12例（85.7％）为从事服装销售的外省来京务工人员,2起暴发疫情间存在流行病学联系.结论 D8基因型麻疹病例为北京市首次监测到的新基因型病例,发病人群主要为外省户籍成年人,并引起局部暴发和本地传播.Objective To investigate the epidemiological characteristics of measles cases of new genotype D8 in Beijing from January to June,2013.Methods Epidemiological survey and descriptive analysis was conducted.Results 661 suspected measles were reported from January to June,2013.416 were confirmed measles cases by serology and etiology detection.28 measles cases were caused by genotype D8 measles virus by genotype identification.There were 2 measles outbreak including 14 cases and 14 sporadic cases.The incidence peak was during April and May.25 cases （89.3%,25/28） occurred in downtown and suburban districts.22 cases （78.5%,22/28） were adults aged 15-39 years and 19 cases （67.9%,19/28） were migrant population.12 cases （85.7%,12/14） in outbreak were migrant population working in clothing sales.There was epidemiological association between 2 outbreaks.Conclusion Measles cases of genotype D8 were found for the first time in Beijing.Genotype D8 virus mainly infected migrant adults and caused local outbreak and endemic.

关 键 词：麻疹 D8基因型 暴发 

分 类 号：R511.1[医药卫生—内科学] R181.3[医药卫生—临床医学]