中国综合性医院院内感染病原菌分布的Meta分析  被引量:24

Distribution of the of nosocomial infection pathogens among general hospital in China: a Meta analysis

在线阅读下载全文

作  者:黄娅铃[1] 张帆[1] 谭斌[1] 张弦[1] 薛健[1] 周锡鹏[1] 李迎丽[1] 邱景富[1] 

机构地区:[1]重庆医科大学公共卫生与管理学院,400016

出  处:《中华流行病学杂志》2013年第11期1134-1138,共5页Chinese Journal of Epidemiology

基  金:国家自然科学基金(31071093,31170129,31200064);重庆市科委攻关项目(2011GGB062)

摘  要:目的 系统评价中国综合性医院院内感染病原菌分布的变化趋势.方法 计算机检索中国生物医学文献数据库、中国期刊全文数据库、维普中文科技期刊全文数据库及万方数据知识服务平台,检索时间为建库至2013年3月,收集有关医院感染调查和研究的相关文献,由2名独立的研究者严格按照纳入和排除标准筛选文献、提取相关数据并采用Comprehensive Meta分析软件进行率的合并分析,将医院感染病原菌按照调查年份、医院等级、医院所在地区进行分层分析,根据异质性检验结果对医院院内感染不同病原菌分布率加权合并.结果 共纳入345篇文献.合并结果显示:(1)1987-2000年真菌检出率为18.6%(95%CI:13.7% ~ 24.9%)、葡萄球菌属为18.1%(95%CI:15.4% ~ 21.0%)、假单胞菌属为14.8%(95%CI:12.2%~ 17.9%)、克雷伯菌属为5.2%(95%CI:4.1%~6.6%);2001-2012年真菌检出率为17.6%(95%CI:16.4% ~ 18.8%)、葡萄球菌属为15.0%(95%CI:14.2%~15.8%)、假单胞菌属为13.9%(95%CI:13.1%~14.7%)、克雷伯菌属为10.4% (95%CI:9.9%~ 11.0%).(2)在二级及以下医院支原体检出率为3.2%(95%CI:0.3%~29.9%)、志贺菌属为4.7%(95%CI:3.4% ~ 6.3%)、产碱杆菌属为7.2% (95%CI:1.7% ~ 26.1%);三级医院支原体检出率为1.1%(95%CI:0.1%~15.4%)、志贺菌属为1.8% (95%CI:0.6% ~ 5.1%)、产碱杆菌属为4.3%(95%CI:2.3%~8.0%).(3)支原体检出率在长江流域经济区为14.3% (95%CI:2.0% ~ 58.1%)、西南经济区为0.3%(95%CI:0.1%~1.1%);棒状杆菌属检出率在长江流域经济区为0.4% (95%CI:0.1% ~ 1.4%)、东南经济区为9.5%(95%CI:2.4% ~ 31.1%);嗜血杆菌属检出率在北方经济区为0.5%(95%CI:0.2% ~ 0.9%)、东南�Objective To provide basic and direction for nosocomial infection prevention and control through evaluation the distribution of nosocomial infection pathogens and understand current situation of pathogens among general hospital in China.Methods Articles were searched and collected from CBM,CNKI,VIP database and Wanfang database published between creating database to March.2013 about investigation of nosocomial infection.Those literatures were screened and extracted according to the inclusion and exclusion criteria by two reviewers independently.The analysis of pathogens distribution was performed by using comprehensive Meta analysis software and stratified by factor as year,hospital level and region of the study.The distribution rate of different pathogens were merged according to statistical tests for the heterogeneity test.Results The 345 trials were included.The results show 1) the pooled distribution rates of common pathogens in 1987-2000 were as follows:18.6% (95%CI:13.7%-24.9%),18.1% (95%CI:15.4%-21.0%),14.8% (95%CI:12.2%-17.9%),5.2% (95% CI:4.1%-6.6%) for Fungus,Staphylococcus,Pseudomonas,and Klebsiella respectively; the pooled rates of common pathogens in 2001-2012 were as follows:17.6% (95% CI:16.4%-18.8%),15.0% (95%CI:14.2%-15.8%),13.9% (95%CI:13.1%-14.7%),10.4% (95% CI:9.9%-11.0%) for Fungus,Staphylococcus,Pseudomonas,and Klebsiella respectively.2) The pooled distribution rates of pathogens in second and below grade hospital were 3.2% (95%CI:0.3%-29.9%),4.7% (95% CI:3.4%-6.3%),7.2% (95% CI:1.7%-26.1%) for Mycoplasma,Shigella and Alkaligenes respectively; the pooled distribution rates of pathogens in third grade hospital were 1.1% (95%CI:0.1%-15.4%),1.8% (95% CI:0.6%-5.1%),4.3% (95% CI:2.3%-8.0%) for Mycoplasma,Shigella and Alkaligenes respectively.3) The pooled rate of Mycoplasma for Yangtze River Economic Area was 14.3% (95%CI:2.0%-58.1%) and for Southwest Economic Area was 0.3% (95%CI:0.1%-1.1%).

关 键 词:医院感染 病原菌 META分析 

分 类 号:R181.3[医药卫生—流行病学]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象