维生素D缺乏与儿童代谢综合征关系的研究现状  

Current research on the relationship between vitamin D deficiency and pediatric metabolic syndrome

作　　者：冯海霞[1] 万燕萍[1] 

机构地区：[1]上海交通大学医学院附属仁济医院临床营养科,200125

出　　处：《中华实用儿科临床杂志》2013年第19期1514-1516,共3页Chinese Journal of Applied Clinical Pediatrics

基　　金：基金项目：世界健康基金会资助项目（AFINS-HOPE-2013-06,AFINS-HOPE-2011-03）;上海市小儿消化与营养重点实验室（11DZ2260-500）

摘　　要：维生素D（VitD）为固醇类衍生物，具有抗佝偻病作用，又称抗佝偻病维生素。儿童代谢综合征是一组复杂的、相互关联的、可导致心血管疾病和2型糖尿病发生的危险因素聚集。近年来越来越多的研究表明VitD缺乏与儿童代谢综合征的发病风险存在相关性，由于儿童处于生长发育时期，各年龄阶段代谢指标处于动态变化中，导致其相关程度在儿童这个特殊群体中备受争议，其机制尚未明确。因此，深入研究ViiD缺乏与儿童代谢综合征各组分的关系为通过提高VitD水平早期干预治疗提供理论依据，从而降低儿童代谢综合征的发病风险。Vitamin D（Vit D） belongs to steroids derivative and is also known as anti-rickets vitamin owing to its effect of anti-rickets. Pediatric metabolic syndrome is a group of complex, interrelated accumulation of risk factors that can lead to cardiovascular disease and type 2 diabetes. Recently, more and more reports demonstrate that Vit D de- ficiency is associated with the risk for pediatric metabolic syndrome, but the association is disputed among the children which is a special group since they are in the period of growth and the metabolic indicators are in the dynamic changes among all ages. Therefore, research on the relationship between Vit D and the components of pediatric metabolic syn- drome will provide some theoretical basis for early intervention and treatment by raising the status of serum Vit D in or- der to reduce the risk for pediatric metabolic syndrome.

关 键 词：维生素D缺乏 代谢综合征 肥胖 脂代谢紊乱 高血压 糖代谢异常 儿童 

分 类 号：R725.8[医药卫生—儿科]