Palladium-Catalyzed Desulfitative Cross-Coupling of Sodium Arylsulfinates with Aryl Bromides and Chlorides： An Alternative Convenient Synthesis of Biaryls  

作　　者：Chao Zhou Yarning Li Yang Lu Rong Zhang Kun Jin Xinmei Fu Chunying Duan 

机构地区：[1]State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, Dalian, Liaoning 116024, China

出　　处：《Chinese Journal of Chemistry》2013年第10期1269-1273,共5页中国化学（英文版）

基　　金：Acknowledgement This work was supported by the National Natural Science Foundation of China （Nos. 21176039, 20876021 and 20923006）.

摘　　要：An alternative method for synthesis of biaryls has been developed through the Pd catalyzed desulfitative coupling reaction of sodium arylsulfinates with aryl bromides and chlorides. The procedure tolerates a variety of functional groups, such as cyano, formyl, acetyl, chloro, methoxy, trifluoromethyl and heteroaromatic unit. The desired products were obtained in moderate to excellent yields under relatively mild reaction conditions without additives, base or co-catalyst.An alternative method for synthesis of biaryls has been developed through the Pd catalyzed desulfitative coupling reaction of sodium arylsulfinates with aryl bromides and chlorides. The procedure tolerates a variety of functional groups, such as cyano, formyl, acetyl, chloro, methoxy, trifluoromethyl and heteroaromatic unit. The desired products were obtained in moderate to excellent yields under relatively mild reaction conditions without additives, base or co-catalyst.

关 键 词：CROSS-COUPLING desulfination aryl bromides aryl chlorides PALLADIUM 

分 类 号：O627.42[理学—有机化学] TQ655[理学—化学]