Absolute Configuration of the Phenylpropanoid Isolated from Peperomia tetraphylla  

作　　者：Yanchao Yu Xiaowei Lu Wenju Wu Yikang Wu Bo Liu 

机构地区：[1]Key Laboratory of Green Chemical Technology of College of Heilong/iang Province, School of Chemistry and Environmental Engineering, Harbin University of Science and Technology, Harbin, Heilongjiang 150040, China [2]State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China

出　　处：《Chinese Journal of Chemistry》2013年第10期1336-1340,共5页中国化学（英文版）

基　　金：Acknowledgement This work was supported by the National Basic Research Program of China （the 973 Program, No. 2010CB833200）, the National Natural Science Foundation of China （Nos. 21172247, 21032002, 20921091） and the Chinese Academy of Sciences.

摘　　要：A recently identified phenylpropanoid isolated from Peperomia tetraphylla was synthesized in enantiopure forms using an aldol condensation of enantiopure （R）-N-acetyl 4-phenyl-oxazolidin-2-one as the key step. With the aid of the single crystal X-ray crystallographic analysis of the synthetic sample, the configuration for the natural product was unambiguously established. Corrected/updated ^13C NMR and optical rotation are also presented.A recently identified phenylpropanoid isolated from Peperomia tetraphylla was synthesized in enantiopure forms using an aldol condensation of enantiopure （R）-N-acetyl 4-phenyl-oxazolidin-2-one as the key step. With the aid of the single crystal X-ray crystallographic analysis of the synthetic sample, the configuration for the natural product was unambiguously established. Corrected/updated ^13C NMR and optical rotation are also presented.

关 键 词：ESTERS aldol condensation natural products STEREOCHEMISTRY ETHERS 

分 类 号：O722.7[理学—晶体学] TQ632.4[化学工程—精细化工]