济南市城区健康老年男性骨密度分析  

Analysis of bone mineral density in the elderly men in Jinan

作　　者：康东红[1] 王燕[2] 张洪美[1] 刘涛[1] 冯潇雨[1] 曹维[1] 王萍[1] 

机构地区：[1]山东大学附属千佛山医院内分泌科,济南250014 [2]泰山医学院附属医院内分泌科,泰安271000

出　　处：《中国骨质疏松杂志》2013年第10期1091-1094,1107,共5页Chinese Journal of Osteoporosis

基　　金：山东省自然科学基金项目(2004ZX07);民政部老年学和老年医学"十一五研究计划"(民人教科字[2008]47-1)

摘　　要：目的探讨济南城区健康老年男性骨密度的变化规律，为防治男性骨质疏松提供依据。方法于2010年，随机抽取本院所管辖的3个社区，再随机抽取963名健康成年男性作为研究对象，年龄40～90岁，平均年龄（61．3±13．6）岁。采用双能X线骨密度测量仪（GELunarDPX-NT，USA）检测腰椎1至4联合值、股骨颈、全股骨、挠骨远端和挠尺骨全部的骨密度。结果（1）40岁以后腰椎、股骨及前臂骨密度缓慢下降，70至74岁，股骨颈及挠骨远端骨密度明显降低，与65至69岁比较，差异有显著性（P〈0．05）。（2）股骨颈、股骨全部、挠骨远端、挠尺骨全部骨密度累积丢失率为18．71％、14．80％、20．95％、25．68％。（3）70至79岁骨质疏松和骨量减少的发生率为29．1％和45．3％，80至90岁为50．0％和32．4％。结论男性在70至74岁骨丢失加速，70岁以后骨质疏松发生率明显上升。Objective To investigate the changing pattern of bone mineral density （BMD） in the elderly men in Jinan, in order to provide basis for the prevention and treatment of osteoporosis. Methods Three communities under the adminstration of Qianfoshan Hospital were randomly selected in 2010. Then 963 healthy men were randomly selected in these 3 communities, from 40 to 90 years old, with an average age of 61.3±13.6 years old. BMD of the lumbar vertebrae （L1-4） , the femoral neck, the total femur, the radius distal, and the total radius and the ulna was detected using dual-energy X-ray absorptiometry （ DEXA, Lunar DPX-NT, GE, USA）. Results When above 40 years old, BMD of the lumbar vertebrae, the femur, and the radius and the ulna decreased gradually. While at the age of 70-74 years old, BMD of the femoral neck and the radius distal decreased rapidly. The cumulative loss rate of BMD of the femoral neck, the total femur, the radius distal, and the total radius and the ulna was 18.71% , 14. 80% , 20.95% , and 25.68% , respectively. The incidence of osteoporosis and bone mass loss in subjects between 70 and 79 years old was 29.1% and 45.3% , respectively. The rate in subjects between 80 and 89 years was 50. 0% and 32. 4% , respectively. Conclusion Bone mass loss is accelerated in men between 70 and 74 years old. The incidence of osteoporosis increased significantly in men over 70 years old.

关 键 词：老年 男性 骨密度 

分 类 号：R18[医药卫生—流行病学]