急性百草枯中毒诊治研究进展  

Developments in treatment and diagnosis of acute paraquat poisoning

作　　者：杨志洲[1] 聂时南[1] 

机构地区：[1]南京军区南京总医院急救医学科,南京医学硕士210002

出　　处：《医学研究生学报》2013年第10期1101-1104,共4页Journal of Medical Postgraduates

基　　金：南京军区人才培养"122工程"项目基金(JQZD200905)

摘　　要：急性百草枯中毒是临床致死率较高的农药中毒,它的治疗一直是国内外研究的热点。使用吸附剂减少消化道吸收,早期开始血液灌流或血液灌流加血液透析增加或加快毒物的清除,应用激素、免疫抑制剂和抗氧化剂等是目前研究最多的治疗方法,但总体治疗效果仍不理想。寻找能够抑制肺纤维化的免疫抑制剂、抗氧化剂的治疗方法、组合,可能对于改变患者预后有着良好的前景,但尚需进一步的研究证明。文章针对急性百草枯中毒诊治的研究进展作一综述。Acute paraquat poisoning has a high fatality rate of pesticide poisoning in clinical. Its treatment is a research hots pot at home and abroad. Using adsorbent to reduce gastrointestinal absorption, starting early haemodialysis （HD） or haemoperfusion （HP） and HD to enhance elimination, utilizing immunosuppression and antioxidants are the most studied treatments currently. Al though there are many treatments,the effect is still not ideal overall, Finding correct ways to use immunosuppressants and antioxidants to suppress pulmonary fibrosis may play an important role in changing the prognosis of patients. However, it needs more further resear ches to prove.

关 键 词：百草枯 中毒 治疗 抗氧化剂 免疫抑制剂 

分 类 号：R139.3[医药卫生—劳动卫生]