山东省沂源县西部地区恙虫病东方体、地方性斑疹伤寒和斑点热立克次体血清流行病学的初步研究  

Preliminary research of seroepidemiology on seroprevalence of Orientia tsutsugamushi,Rickettsia typhi and Spotted fever rickettsia in rural populations in the west of Yiyuan,Shandong Province of China

作　　者：迟媛媛[1] 翟慎勇 温红玲[1] 崔峰[2] 王玲[2] 杜俊[2] 王谦[3] 张寿锋 Kandace Schneider 徐文斌 赵丽[1] 于学杰[1,5] 

机构地区：[1]山东大学公共卫生学院微生物检验室,济南250012 [2]淄博市疾病预防控制中心,山东淄博255026 [3]沂源县疾病预防控制中心,山东沂源256100 [4]Biocell Diagnostics,Inc.,Baltimore,MD 21224,USA [5]Department of Pathology and Microbiology,Center for Biodefense and Emerging Infectious Diseases,Institute for Human Infections and Immunity,University of Texas Medical Branch,Galveston,Texas 77555-0609,USA

出　　处：《山东大学学报（医学版）》2013年第10期98-100,104,共4页Journal of Shandong University:Health Sciences

基　　金：山东大学公共卫生学院人才队伍建设基金

摘　　要：目的了解近年山东省沂源县西部地区农村人口恙虫病东方体、地方性斑疹伤寒立克次体和斑点热立克次体的感染情况,为自然疫源性疾病的预防和控制提供依据。方法 2011年从山东省沂源县西部乡镇的农村人口中随机收集192份血清,采用间接免疫荧光法检测血清中恙虫病东方体、地方性斑疹伤寒立克次体和斑点热立克次体抗体。结果恙虫病东方体、地方性斑疹伤寒立克次体和斑点热立克次体抗体血清阳性率分别为56.77%(109/192)、79.69%(153/192)和69.79%(134/192)。结论山东省沂源县西部农村人口中恙虫病东方体、地方性斑疹伤寒立克次体和斑点热立克次体的感染率较高。Objective To study the rickettsial disease infection situation in rural populations in the west of Yiyuan and pro- vide scientific basis to control and prevent natural focal diseases. Methods We collected 192 sera from farmers in the west of Yiyuan County, Shandong Province and tested them by indirect-immunofluorescence assay （IFA） for antibodies of Orientia tsutsugamushi, Rickettsia typhi and Spotted fever rickettsia. Results 56.77% （ 109/192）, 79.69% （ 153/ 192） and 69.79% （134/192） sera were positive for antibodies of Orientia tsutsugamushi, Rickettsia typhi and Spotted fever rickettsia, respectively. Conclusion The results indicate high prevalences of these rickettsial diseases in this area.

关 键 词：恙虫病 地方性斑疹伤寒 斑点热 血清抗体阳性率 

分 类 号：R513[医药卫生—内科学]