降脂药物与静脉血栓栓塞症的相关性研究  

lationship between statins and venous thromboembolism

作　　者：高秀玲[1] 杨在利[1] 崔朝勃[1] 张会英[1] 高春蕾[1] 韩东亮[1] 

机构地区：[1]河北医科大学附属衡水市哈励逊国际医院呼吸科,053000

出　　处：《国际呼吸杂志》2013年第20期1525-1528,共4页International Journal of Respiration

摘　　要：目的探讨他汀类降脂药物与静脉血栓栓塞症（VTE）发生的关系。方法选择3000名健康体检者，他们只有血脂异常，不合并其他疾病。随机分为观察组和对照组，观察组给予他汀类降脂药物＋饮食控制＋运动疗法治疗，对照组给予饮食控制＋运动疗法。1年后观察两组发生VTE的情况，进行统计学分析，其中合并其他疾病及死亡的被排除在外。结果两组的年龄、性别、入组前的血脂水平差异无统计学意义；对照组有7名发生VTE，而观察组有2名发生VTE，两组发生率差异有统计学意义（P〈0．05）。结论他汀类降脂药物有降低VTE发生的作用。[Abstract] Objective To study the relationship between statins and venous thromboembolism （VTE）. Methods 3 000 individuals with dyslipidemia were selected,and they had no other diseases. The individuals were randomly divided into two groups：observation group was given statins,controling food, and moving,control group was given controling food and moving therapy. After one year, the number of cases of VTE in the two groups was observed and compared with statistical analysis. Results There was no statistical significanse in age, sex, and blood lipid level between the two groups. Seven individuals occurred VTE in control group and two individuals occurred VTE in observation group. There was statistical significance in incidence rate of VTE between the two groups （ P 〈0.05）. Conclusions Statins i. can decrease the occurrence of vTE.

关 键 词：他汀类降脂药物 静脉血栓栓塞症 

分 类 号：R543.6[医药卫生—心血管疾病]