针刺合耳穴贴压治疗多囊卵巢综合征疗效及安全性评价  

Efficacy and safety evaluation of acupuncture combined with auricular point sticking therapy in the treatment of polycystic ovary syndrome

作　　者：李宁[1] 

机构地区：[1]首都医科大学附属北京妇产医院理疗针灸科,北京100026

出　　处：《中国针灸》2013年第11期961-964,共4页Chinese Acupuncture & Moxibustion

基　　金：首都医科大学附属北京妇产医院科研基金资助项目:201101

摘　　要：目的:比较针刺配合耳穴贴压法与西药克罗米芬治疗多囊卵巢综合征排卵障碍的疗效差异。方法:将100例多囊卵巢综合征患者随机分为两组,每组50例。针刺耳压组:体针穴取关元、中极、子宫等为主,每天1次;耳穴贴压取脾、内分泌、子宫、肾等穴,每周换贴1次。一个月为一疗程,共3个疗程。克罗米芬组:于经期第5日口服克罗米芬50mg,连服5天,连续治疗3个月经周期。观察两组促排卵、妊娠及恢复月经周期情况,并比较两组疗效。结果:针刺耳压组的总有效率为90.0%(45/50)高于克罗米芬组的86.0%(43/50),P<0.05;针刺耳压组排卵率和妊娠率分别为68.0%(34/50)和64.0%(32/50),与克罗米芬组相比均P<0.05;针刺耳压组和克罗米芬组月经周期恢复正常率分别为94.0%(47/50)和88.0%(44/50),针刺耳压组优于克罗米芬组(P<0.05)。针刺耳压组患者未发现不良反应;克罗米芬组有29例患者出现不同程度的恶心、呕吐、头痛、皮炎等不良反应,14例患者B超监测有卵巢增大等过度刺激综合征(OHSS)征象。结论:针刺耳压法治疗多囊卵巢综合征排卵障碍的临床疗效明显优于单纯使用西药克罗米芬,且安全、无不良反应。Objective To compare the efficacy differences between acupuncture combined with auricular point sticking therapy and clomiphene oral administration in the treatment of polycystic ovary syndrome （PCOS）. Methods One hundred cases of PCOS were randomized into two groups, 50 cases in each one. Acupuncture com- bined with auricular point sticking group （group A）： acupuncture was applied at Guanyuan （CV 4）, Zhongji （CV 3） and Zigong （EX-CA 1）, once daily. auricular point sticking was applied at Spleen （pi, CO13）, Endocrine （neifenmi, CO18）, Unterus and Kidney （shen, CO10）, the plaster was changed once a week. Clomiphene group （group B） ： oral clomiphene was prescribed at the 5th day of the menstrual, for 5 consecutive days, totally 3 menstrual cycles was needed. The ovulation induction, pregnancy and menstruation resuming of patients in the two group were observed and compared. Results The totally effective rate was 90.0%（45/50） in group A, which was superior to 86.0% （43/50） in group B （P〈0.05） . the ovulation rate and pregnancy rate were 68.0% （34/50）and 64.0% （32/50） in group A, whiche were superior to that of group B （all P〈0. 05） % the menstruation resuming rate was 94.0% （47/50） in group A, which was superior to 88.0V00 （44/50） in group B （P〈0.05）. No adverse effect was observed in group A, while in group B, varying degrees of nausea, vomiting, headache and dermatitis were observed in 29 cases, ovarian hyperstimulation syndrome （OHSS） like polycystic ovary was observed in 14 cases under the B ultrasound. Conclusion Acupuncture combined with auricular point sticking therapy has a better effect than clomiphene in the treatment of PCOS without any adverse effect.

关 键 词：多囊卵巢综合征 排卵障碍 针刺疗法 耳穴贴压 

分 类 号：R246.3[医药卫生—针灸推拿学]