PET在神经精神疾病领域中的应用进展  

The Applications of Positron Emission Tomography in Neurological and Psychiatric Disorders

作　　者：张慧玮[1] 左传涛[1] 许震生[1] 

机构地区：[1]复旦大学附属华山医院PET中心,上海200235

出　　处：《中国医疗器械信息》2013年第10期1-8,共8页China Medical Device Information

基　　金：国家自然科学基金面上项目(81171189;81271516)

摘　　要：PET作为功能性分子成像的主要工具,在帕金森病及阿尔茨海默等神经退行性疾病、精神障碍、脑肿瘤、癫痫、脑血管疾病等方面扮演了重要角色。尽管脑PET显像在神经精神疾病临床应用方面已经取得了长足的进步,但考虑到其独特的功能成像优势和转化医学的发展,PET仍没有发掘出全部潜力。今后脑PET显像可能的发展方向:仪器的发展;新型示踪剂的研究;脑生理激发试验的深入;神经传导通路和神经生理的研究;精神疾病的研究等。Positron emission tomography （PET） is a major tool for functional molecular imaging and plays an important role in the study of brain function, epilepsy as well as neurodegenerative diseases such as Parkinson＇s disease and Alzheimer＇s disease. However, despite its unique strengths and in view of the present needs in translational experimental medicine, PET is currently not achieving its full potential in brain research and clinical application. In the thture, the potentials of brain PET include development of the instrument, new tracers, further brain physiological provocation test, nerve conduction pathways and neurophysiological studies and mental illness.

关 键 词：正电子断层显像 阿尔茨海默病 帕金森病 癫痫 精神分裂症 

分 类 号：R817.4[医药卫生—影像医学与核医学]