4位卤素取代的邻苯二甲酰胺类化合物的杀虫活性  

4-Halogen Phthalic Diamides with High Insecticidal Activities

作　　者：鲍樟水[1] 朱冰春[1] 韦伟[1] 魏优昌[1] 孔小林[1] 

机构地区：[1]浙江省化工研究院有限公司,浙江杭州310023

出　　处：《浙江化工》2013年第10期3-6,共4页Zhejiang Chemical Industry

基　　金："十二五"国家科技支撑计划项目(2011BAE06B01-20);国家自然科学基金项目(21202151);浙江省重点科技创新团队项目(2010R50018)

摘　　要：以4位卤素取代的邻苯二甲酸酐,2-氨基-2-甲基丙腈和全氟异丙基苯胺为起始原料,合成了14个未见文献报道的4位卤素取代的含七氟异丙基的新型邻苯二甲酰胺类化合物。通过1H NMR和ESI-MS确定了中间体和目标化合物的结构。生物活性测试表明,此类化合物对鳞翅目害虫具有非常好的杀虫活性,其中化合物5c和5n在0.8 mg/L质量浓度下对小菜蛾(Plutella xylostella)的致死率仍然达到100%。14 novel 4-halogan phthalic diamides containing heptafluoroisopropyl were synthesized by using substituted 4-halogan phthalic anhydride, 2-amino-2-methylpropionitrile and heptafluoroisopropyl aniline as starting materials. The structures of intermediates and target compounds were confirmed by ^1H NMR and ESI-MS. The bioassays showed that these compounds possessed good insecticidal activities against lepidoptera pests. The mortality ratio of compounds 5c and 5n against Plutella xylostella were 100% at the concentration of 0.8 mg/L.

关 键 词：邻苯二甲酰胺 卤素 全氟异丙基苯胺 合成 杀虫活性 

分 类 号：TQ453[化学工程—农药化工]