丝素组织工程支架的结构相容性与细胞相容性  

Research on Structure Biocompatibility and Cell Biocompatibility of Silk Fibroin Scaffolds for Tissue Engineering

作　　者：刘小甜[1] 杨明英[1] 邓连霞[1] 朱良均[1] 

机构地区：[1]浙江大学动物科学学院应用生物资源研究所,浙江杭州310058

出　　处：《蚕桑通报》2013年第3期15-17,共3页Bulletin of Sericulture

摘　　要：丝素蛋白是一种天然的纤维蛋白,具有良好的生物相容性、生物降解性、可加工性、机械性能等优点,为丝素蛋白生物材料的开发提供了条件。由于受损组织的修复是一个非常复杂的过程,因此,组织工程用支架对生物材料的性能要求也异常严格和复杂。目前,丝素蛋白结构相容性和细胞相容性方面的研究取得了一定的进展,对促进丝素蛋白在组织工程领域内的应用具有重要意义。Silk fibroin is a natural biomaterial protein due to its excellent biocompatibility, biodegradability, mechanical property and processibility. The properties of biomaterial scaffolds are quite strict and complex for its practical applica- tion in tissue engineering. Recently, many researches on structure biocompatihility and cell biocompatibility of silk fibro- in have been conducted. The results showed good biocompatibility of fibroin, which is important for promoting the appli- cation of fibroin in tissue engineering.

关 键 词：丝素 组织工程支架 结构相容性 细胞相容性 

分 类 号：R318.08[医药卫生—生物医学工程]