检测血清降钙素原与超敏C反应蛋白在诊断儿童急性呼吸道感染中应用价值  

Combined application value analysis of detecting serum levels of PCT and hs-CRP in children with acute respiratory tract infection

作　　者：黄杰[1] 陈鑫[1] 王占科[1] 刘亚成[2] 叶心周[1] 宁丽萍[1] 梁建斌[3] 

机构地区：[1]解放军第九四医院检验科,江西南昌330002 [2]江西省人民医院检验科,江西南昌330006 [3]解放军第九四医院妇儿中心,江西南昌330002

出　　处：《临床和实验医学杂志》2013年第20期1645-1646,共2页Journal of Clinical and Experimental Medicine

基　　金：国家科技支撑课题;2008BAI52B03

摘　　要：目的探讨检测血清降钙素原(PCT)与超敏C反应蛋白(hs-CRP)水平在诊断小儿急性呼吸道感染中的临床意义。方法急性呼吸道感染组84例患儿(细菌感染组44例,病毒感染组40例),40例健康体检儿童为正常对照组,检测两组血清PCT与hs-CRP水平,并比较差异。结果急性呼吸道感染组血清PCT与hs-CRP水平均显著高于正常对照组(P<0.01);细菌感染组血清PCT与hs-CRP水平显著高于病毒感染组(P<0.05);急性呼吸道感染患儿血清PCT与hs-CRP水平之间呈正性显著相关(P<0.05)。结论测定血清PCT与hs-CRP水平对实验诊断儿童急性呼吸道感染具有重要意义。Objective To explore the clinical significance of detecting the serum levels of PCT and hs CRP in children with acute re spiratory tract infection （ARI）. Methods The serum levels of PCT and hs CRP were detected in 84 patients （44 children with bacterial infec tion, 40 children with virus infection）. The levels of these patients were compared with those of 40 healthy children. Results The serum levels of PCT and hs CRP in ARI group were significantly higher than those in the control group. The difference was statistically significant （ P 〈0.05 or P 〈0. 01 ）. The serum levels of PCT and hs CRP in the bacterial infection group were significantly higher than those in the virus infection group. The difference was statistically significant （ P 〈 0.05 ）. The serum levels of PCT and hs CRP were actively correlated each other （ P 〈 0.05 ）. Conclusion The co detection of serum levels of PCT and hs CRP play an important role in diagnosing ARI in children patient.

关 键 词：小儿 急性呼吸道感染 血清降钙素原 超敏C反应蛋白 

分 类 号：R725.6[医药卫生—儿科]