某医院感染葡萄球菌的临床分布及耐药性分析  

The Analysis of Clinical Distribution of MRSA and MRSE Infection and Drug-resistance

作　　者：李晓勤[1] 朱娜[1] 孙丽婷[1] 李巍[2] 

机构地区：[1]乌鲁木齐市第四人民医院检验科,乌鲁木齐830002 [2]新疆医科大学第一附属医院检验科,乌鲁木齐830011

出　　处：《新疆医科大学学报》2013年第10期1491-1493,共3页Journal of Xinjiang Medical University

基　　金：新疆维吾尔自治区自然科学基金(2012211B33)

摘　　要：目的了解耐甲氧西林金葡菌(MRSA)和凝固酶阴性葡萄球菌(MRSE)的临床分布及其耐药性,指导临床合理使用抗菌药物。方法对2012年1月-2013年1月乌鲁木齐市第四人民医院临床分离的146株MRSA和121株MRSE的临床分布和耐药率进行统计学分析。结果 146株MRSA和121株MRSE的分布主要以痰标本为主(44.5%和42.9%),其次为尿液(15.7%和16.5%)。MRSA和MRSE对苯唑西林和青霉素的耐药率最高,分别为100.00%和92.56%、100.00%和96.70%,其次为红霉素(85.62%和88.43%),而对万古霉素和利奈唑烷的耐药率为0.00%。结论医院感染MRSA和MRSE对所测抗菌药物均有不同程度的耐药,医院应加强对药品的管理和定期进行耐药性检测,指导临床合理用药。Objective To understand the clinical distribution and antimicrobial resistanse of Staphylococcus and to guide clinical rational use of antibiotics.Methods We analyzed the clinical distribution and drug re-sistance of Staphylococcus in 146 and 121 Laboratory strains of MRSA and MRSE extracted by the re-searchers from January 2012 to January 2013.Results The distribution of Staphylococcus was mainly in Phegm（44.5% ,42.9%）,in midstream urine （15.7% ,16.5%）secondly.Anitimicrobial resistance rate of MRSA and MRSE to Oxacillin and Penicillin was the highest（100% and 96.70%,92.56%）,but that to Vancomycin and Linezolid was 0.00%.Conclusion Hospital infection with MRSA and MRSE was resistant to certain drugs.It is suggested that the use of drugs be supervised strictly,that the drug resist-ance should be tested regularly.

关 键 词：耐甲氧西林金葡菌 凝固酶阴性葡萄球菌 耐药率 抗生素 

分 类 号：R446.5[医药卫生—诊断学]