系统化护理干预对癌因性疲乏患者影响的Meta分析  

Meta-Analysis of Systematic Nursing Intervention on Patients with Cancer Related Fatigue

作　　者：阿依古丽.买买提 佟宛云[2] 韩记真[3] 

机构地区：[1]新疆医科大学附属肿瘤医院肺内二科,乌鲁木齐830011 [2]新疆医科大学附属肿瘤医院特需科,乌鲁木齐830011 [3]新疆医科大学附属肿瘤医院门诊,乌鲁木齐830011

出　　处：《新疆医科大学学报》2013年第10期1539-1542,1545,共5页Journal of Xinjiang Medical University

基　　金：新疆维吾尔自治区自然科学基金(2012211A047)

摘　　要：目的系统评价系统化护理干预对癌因性疲乏(cancer-related fatigue,CRF)患者的影响。方法以"癌症"、"疲乏"、"系统化护理"等为关键词,计算机检索中国生物医学文献数据库(CBM)、中国期刊全文数据库(CNKI)、维普数据库(VIP)及万方数据库,检索日期为数据库建立至2012年12月1日;纳入系统化护理干预CRF患者的随机对照试验(RCT),由2名评价者独立评价纳入研究的质量并提取资料,并用RevMan 5.0统计软件进行Meta分析。结果共纳入9篇文献,包括1 042例CRF患者,所有研究均采用了随机对照的方法,但未明确是否采用分配隐藏或双盲。Meta分析结果显示,通过护理干预后,系统护理干预组无疲乏及轻度疲乏患者明显多于常规护理组,差异具有统计学意义(RR合并=4.72,P<0.01,95%CI=3.58～6.24);系统化护理对CRF患者的生活质量的影响,与常规护理比较,差异具有统计学意义(RR合并=9.67,P=0.003,95%CI=3.30～16.04);经干预后系统化护理组CRF患者的卡氏功能(KPS)评分明显低于常规护理组患者,差异具有统计学意义(RR合并=4.22,P<0.01,95%CI=2.06～6.38)。结论针对CRF患者进行护理,系统化护理干预明显优于常规护理模式,可改善CRF患者疲乏状态、生活质量等。Objective To evaluate the systematic nursing intervention on patients with cancer related fatigue（Cancer-related Fatigue CRF）.Methods “Cancer”,“Fatigue”,“Systematic Nursing”as key words, computer retrieval Chinese Biomedical Literature Database （CBM）,Chinese Journal Full-text Database （CNKI）,VIP database（VIP）and Wanfang database,retrieve date established for the database to Decem-ber 1,2012;systematic nursing intervention in patients with CRF included randomized controlled trials （RCT）,2 reviewers independently evaluated the quality of included studies and extracted data,and use RevMan 5.0 statistical software for Meta-analysis.Results A total of nine documents,including 1 042 pa-tients with CRF, all studies using a randomized controlled way, but was not clear whether to use allocation concealment or blinded.Meta-analysis showed that,through nursing intervention,the system nursing intervention group patients without fatigue and mild fatigue,significantly more than usual care group,the difference was statistically significant （RR combined=4.72,P 〈0.01,95%CI =3.58-6.24）;systematic care for the quality of life in patients with CRF effects compared with usual care,the difference was statistically significant （RR combined=9.67,P =0.003,95%CI =3.30-16.04）;through systematic care group after intervention Cartesian function in patients with CRF（KPS）score was significantly lower than usual care patients,the difference was statistically significant （RR combined=4.22,P 〈0.01,95%CI =2.06-6.38）.Conclusion For patients with CRF for care,systematic nursing intervention was signifi-cantly better than the conventional model of care,which can improve fatigue in patients with CRF status, quality of life and so on.

关 键 词：癌症 疲乏 系统化护理 META分析 

分 类 号：R473.73[医药卫生—护理学]