骨髓腔穿刺输液途径抢救产后大出血休克  

Bone marrow infusion for rescue therapy of postpartum massive hemorrhage

作　　者：刘凤华 

机构地区：[1]焦作市第五人民医院妇产科,河南焦作454000

出　　处：《广州医学院学报》2013年第3期60-62,共3页Academic Journal of Guangzhou Medical College

摘　　要：目的:观察实施骨髓腔穿刺输液途径抢救产后大出血休克的临床疗效。方法:将78例产后大出血患者设为观察组,另通过回顾性医疗文献收集80例情况类似的患者设为对照组。对照组采用传统静脉穿刺输液途径,观察组实施骨髓腔穿刺输液途径。观察入院抢救开始至输液通道建成时间、开始抢救及从急救输液通道用药至血压回升时间、抢救4h内疗效、病死率等指标。结果:观察组建立通道时间、血压回升时间2项指标均低于对照组(P<0.01);观察组血压回升数值和每小时尿量均高于对照组(P<0.01);动脉血氧饱和度和静脉血氧饱和度均差异有统计学意义(P<0.01);观察组组织缺氧情况的改善优于对照组(P<0.01);观察组患者病死率低于对照组(P<0.01)。结论:骨髓腔穿刺输液途径作为常规选择方案用于抢救产后大出血休克,可提高抢救治疗效果,降低病死率。Objective：To determine the efficacy of bone marrow infusion for rescue therapy of postpartum massive hemorrhage. Methods： We enrolled 78 females with postpartum massive hemorrhage（ observation group） and retrospectively retrieved the clinical profiles of 80 females who encountered with similar conditions by literature review （control group ）. Bone marrow infusion was conducted in the observation group. This entailed analysis on the duration from in-hospital rescue therapy to the establishment of infusion channel, from rescue therapy or administration of medications to recovery of blood pressure, efficacy within 4 hours and the mortality. Results ： The observation group yielded a shortened duration to establish the infusion channel and recovery of the blood pressure（ both P 〈 0.01 ）. Apart from a higher increase in the blood pressure and urine volume per hour,the observation g}oup was associated with significantly improved arterial and venous oxygen saturation and amelioration of tissue hypoxia yet lower mortality（ all P 〈 0.01 ）. Conclusion ： Bone marrow infusion is linked to improved outcomes of rescue therapy and reduced mortality as a conventional approach for the treatment of postpartum massive hemorrhage.

关 键 词：产后大出血 骨髓穿刺输液 静脉穿刺输液 

分 类 号：R714[医药卫生—妇产科学]