关注非甾体类抗炎药在眼表炎症中的正确应用  

Paying attention to the correct application of non-steroidal anti-inflammatory drugs in the treatment of ocular surface inflammatory disease

作　　者：张明昌[1] 张洁[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院眼科,武汉430022

出　　处：《中华实验眼科杂志》2013年第11期1001-1002,共2页Chinese Journal Of Experimental Ophthalmology

摘　　要：炎症是眼表的常见疾病。糖皮质激素类药物治疗眼表炎症的疗效确切，但局部长期及大量应用此类药物易发生严重的不良反应。非甾体类抗炎药（NSAIDs）具有抗炎、抗过敏、止痛等作用，局部应用可预防和治疗眼部多种原因导致的炎症性疾病，不良反应较少，临床应用比糖皮质激素更安全，因此近年来在眼表炎症的治疗中日益受到重视。虽然NSAIDs抗炎作用强，不良反应少，但在临床应用过程中也需根据病情正确选择使用，在一些炎症性眼表疾病治疗过程中需与糖皮质激素药物联合应用，以加强疗效并减少药物不良反应的发生。Inflammation is a common ocular surface disease. Glucocorticoid drugs are effective on the ocular surface inflammation,but their long-term and massive application is prone to serious side effects. Nonsteroidal antiinflammatory drugs （ NSAIDs ） have anti-inflammatory, anti-allergic, analgesic effects. The topical application of NSAIDs for the prevention and treatment of ocular inflammatory disease is much safer than that of glucocorticoid. Therefore, NSAIDs have more and more concerns in the treatment of ocular surface inflammation in recent years. Although NSAID has good anti-inflammatory effectiveness and less adverse effects,it should be correctly administered. During the treatment process of inflammatory ocular surface diseases, the combination of NSAIDs with glucocorticoid drug can strengthen the curative effect and reduce the adverse reactions.

关 键 词：眼表 炎症 非甾体类抗炎药 糖皮质激素 

分 类 号：R971.1[医药卫生—药品]