益气解毒颗粒对鼻咽癌高危人群EB病毒感染活性抑制作用的临床观察  

A Clinical Observation on the Inhibitory Effect of Yiqijiedu Granules to the Infection Activity of EBV in Population Highly Susceptible to NPC

作　　者：田道法[1] 唐发清[2] 陈协云[1] 江永忠[1] 

机构地区：[1]湖南中医学院第一附属医院,湖南长沙410007 [2]湖南医科大学湘雅医院,湖南长沙410078

出　　处：《湖南中医学院学报》2000年第3期47-49,共3页Journal of Hunan College of Traditional Chinese Medicine

基　　金：国家自然科学基金资!助项目 (39770 933) ;国家中医药管理局资助!项目 (95B0 6 3) ;湖南省中医管理局资助!项目 (980 70 )

摘　　要：为观察益气解毒颗粒对鼻咽癌高危人群EB病毒感染活性的抑制作用。将 111例鼻咽癌高危患者随机分为 2组 ,分别予益气解毒颗粒及鼻咽清毒剂 ,连用 3月 ,观察其对壳抗原抗体 (IgA/VCA)和早期抗原抗体(IgA/EA)滴度的影响。结果 :治疗组IgA/VCA由 2 1.485± 2 .95 6降至 3 .6 78± 3.82 1,IgA/EA由 6 .987± 1.5 75降至 1.771± 2 .40 7,显效率 5 1.72 % ,总有效率 87.93% ;对照组则分别由 2 1.793± 3.0 94降至 15 .139± 3 .375 ,7.5 98± 1.732降至 5 .438± 2 .32 9,显效率 7.5 5 % ;总有效率 2 4.5 3% ,组间差异均为P <0 0 1。结论 :益气解毒颗粒对鼻咽癌高危者EB病毒感染活性有很强的抑制作用。To investigate the inhinbitory effect of Yiqijiedu Granules on the infection activity of EBV in population highly susceptible to nasopharyngeal carcinoma (NPC).111 cases were randomly divided into two groups,given Yiqdjiedu Granules (treating group,TG) and Biyanqindu Granules (controlling group CG) respectively for 3 months.Serum samples of the cases were tested to value the level changes of EBV-related antibodies IgA/VCA and IgA /EA .Results:Significantly effective rates and total effective rates for TG and CG were 51.72%,87.93%,and 7.55%,24.53% respectively. Conclusion:Yiqijiedu Granules are significantly effective to inhibit the infection activty of EBV in cases highly susceptible to NPC.

关 键 词：益气解毒颗粒 病毒相关抗体 鼻咽癌 中医药疗法 

分 类 号：R273.965[医药卫生—中西医结合] R285.6[医药卫生—中医肿瘤科]