80岁以上高血压患者合并高脂血症对颈动脉内中膜厚度的影响  

The effects of hyperlipidemia on carotid intima-media thickness in hypertension patients at 80 years or elder

作　　者：司一民[1] 杨娜[1] 张伟伟[1] 乔延国[1] 刘燕[2] 

机构地区：[1]中国人民武装警察部队总医院南二科,北京100039 [2]中国人民武装警察部队总医院干三科,北京100039

出　　处：《中国急救复苏与灾害医学杂志》2013年第10期900-902,共3页China Journal of Emergency Resuscitation and Disaster Medicine

摘　　要：目的研究80岁以上高血压患者合并高脂血症对颈动脉内中膜厚度的影响。方法从体检人群中收集高血压合并高脂血症患者52例作为研究组，按性别、年龄、血压匹配随机抽取单纯高血压患者38例作为对照组。收集年龄、高血压病程、收缩压、舒张压、血糖、甘油三酯、低密度脂蛋白、高密度脂蛋白、总胆固醇、颈动脉内中膜厚度等指标，比较两组间各指标的差异，P〈0．05作为有统计学差异。结果两组之间年龄、病程、血糖、收缩压、舒张压差异无统计学意义（P〉0．05）。高血压合并高脂血症组TG、TC、LDLC及HDLC与单纯高血压组差异具有显著性，高血压合并高脂血症组大于单纯高血压组（P〈0．05）。单纯高血压组和高血压合并高脂血症组颈动脉内中膜厚度差异具有显著性，高血压合并高脂血症颈动脉内中膜厚度（1．12±0．20mm）明显高于单纯高血压组（0．98±0．34mm）（t=2．448，P=0．016〈0．05）。结论高血脂与颈动脉内中膜厚度正相关，高脂血症加速了高血压病患者的动脉硬化，应引起足够的重视。Objective To study the effects of hypedipidemia on carotid intima media thickness （CAIMT） in Hypertension patients at 80 years or elder. Methods 52 hypertension patients with byperlipidemia were selected into the study group, while 38 hypertension patients with similar age and blood pressure history were selected into the control group. The data of age, clinical history, systolic blood pressure （SBP）, diastolic blood pressure （DBP）, blood sugar（BS）, triglyceride （TG）, total cholesterol （TC）, high-density lipoprotein cholesterol （HDLC）, low-density lipoprotein cholesterol （LDLC）, and CAIMT were collected and compared respectively between the two groups. Results No significant difference on sex, age, blood pressure, and BS were found between two groups （P〈 0.05）; yet, it reflected significant difference between the two groups on TG, TC, HDLC and LDLC （P 〈0.05）. The CAIMT （1.12±0.20mm） in the study group was significantly higher than that in hypertensive patients group （0.98 ± 0.34mm） （t=2.448, P =0.016〈 0.05）. Conclusion Lipids are relevant to CAIMT, and hyperlipidemia accelerated arteriosclerosis in the patients with hypertension at 80 years or eider.

关 键 词：老年 高血压 高血脂 颈动脉内中膜厚度 

分 类 号：R543.3[医药卫生—心血管疾病]